In 1653 Father Bernabe Cobo, a chronicler with the Spanish conquest, described Maca as growing in the harshest, coldest regions where no other plant for man's sustenance could be grown. Maca was utilized as a medicinal food by the people of the high altitude Andes regions of Peru and Bolivia and was an important staple of their diet as it is able to grow wild and survive the harsh climates. Maca supported the people to adapt, reproduce, and thrive in harsh conditions that include extreme cold, rugged terrain, low oxygen, intense sunlight and strong winds. Maca was often dried after harvesting to allow for long term storage, and rehydrated as needed. Traditional drying methods that involve outdoor drying in the high elevations of the Andes over about 8 weeks, expose the roots to extreme temperature variations that damage the tissues as water is gradually lost. This tissue damage leads to the release of hydrolytic enzymes which generate bioactive compounds such as macamides and isothiocyanates. The enzymes are deactivated in the dried root, so industrial drying methods that process the fresh roots immediately do not allow for the release of the bioactive compounds. Cooking also destroys these enzymes, which reduces the formation of bioactivity. Maca root has been touted to normalize energy levels and endurance and support a healthy libido, which has been demonstrated in several clinical trials. In as little as two weeks, Maca supplementation was found to significantly improve trial times, as well as increase sexual desire in adult male cyclists. Other studies have shown Maca supplementation to support a healthy mood and blood pressure in postmenopausal women. Maca supplementation was also found to reduce levels of IL-6, an inflammatory biomarker, in as little as one week.