When is the Best Time to Take Ashwagandha?

By Kristen Boye BS, Natural Health

Kristen Boye

Kristen Boye is a natural health expert, writer, copywriter, and editor. Kristen was raised on an organic farm in British Columbia which inspired her life’s work. She holds a Bachelor’s Degree in Natural Health, is a Certified Natural Foods Chef, co-owner of a medicinal herb farm, and is a natural foods and children’s health advocate. Kristen lives with her husband and two children on their medicinal herb farm in Western North Carolina.

https://www.holisticwritingconcepts.com
When is the Best Time to Take Ashwagandha?
When is the Best Time to Take Ashwagandha?

Ashwagandha, also known as Ashwagandha Root, Indian Ginseng, Winter Cherry, or Withania somnifera, is a popular herb for supporting stress response, hormonal balance, sleep, mental well-being, and more.* REF#380

If you’re reading this article, you’re likely familiar with this herb and trying to determine when to take Ashwagandha for the best results.

The short answer is: It may not matter when you take Ashwagandha as long as you take the right amount and practice consistency.

However, timing your Ashwagandha dosage can make all the difference in achieving the results you want.

This article will examine the latest science and research on determining the best time of day to take Ashwagandha, including: 

  • How to find a clean and authentic Ashwagandha supplement 
  • Information on optimal dosage
  • When to take Ashwagandha for specific health concerns*
  • How long it takes to see results*

How to Find a Clean and Authentic Ashwagandha Supplement

Before we talk about the best time to take Ashwagandha, it’s important to know how to find a high-quality supplement.

Unfortunately, Ashwagandha’s recent surge in popularity has led many growers and manufacturers to cut corners in producing quality products.

This could mean raw materials are being grown in an artificial environment with excess pesticides and herbicides, resulting in an inferior product. 

It could also mean manufacturers are skipping proper safety testing for identity, contaminants, and potency. 

Therefore, when buying any herbal supplement, it is crucial to look for an authentic, clean, and potent product from a trusted source.

Here’s what to look for in a high-quality Ashwagandha supplement:

  • No artificial flavors, colors, preservatives, or fillers.
  • Full-spectrum Ashwagandha root and root extract provide the maximum benefit from the herb.
  • Third-Party Certified Organic.
  • Third-party testing for identity, purity, and contaminants such as heavy metals, mold and mildew, pesticide residues, and more.
  • Transparency in sourcing: Gaia Herbs' “Meet Your Herbs” traceability platform, for example, allows you to see exactly where the herbs in a specific formula were grown and sourced.

Gaia Herbs offers several Ashwagandha supplements that meet this criterion, including:

Our Ashwagandha supplements also contain standardized amounts of withanolides, the active plant component responsible for many of its beneficial properties. REF#381

Whether you’re interested in an Ashwagandha tincture, capsule, gummy, or powder, the above criterion will help you avoid potential quality and potency issues.

How to Dose Ashwagandha

Determining the best Ashwagandha dosage for your needs isn’t an exact science.

Always check with your doctor or healthcare practitioner if you’re unsure how much Ashwagandha to take for a specific health concern.

For general dosing, we can draw from traditional use and modern research to determine a reasonable starting point.

  • Traditional Ayurvedic practitioners of the past did not use a standardized dosage for every person. Typically, formulas were tailored to the individual.
  • Recent studies on Ashwagandha for various health concerns used an extract dosed at 250–600 mg daily. 
  • The most common dosage used in studies is 300 mg twice daily (once in the morning and once in the evening) for a total of 600 mg. 
  • Research has shown full-spectrum Ashwagandha is generally safe to take even at higher doses and rarely interacts with most medications. REF#382 REF#383 REF#384 REF#385 REF#386

However, we don’t know the side effects of taking it for longer than eight months at a time.

Always talk to your doctor if you’re taking medications, have an allergy or sensitivity to nightshades, or have a chronic condition before taking Ashwagandha.

The best Ashwagandha dosage depends on various factors, including: 

  • The type of Ashwagandha: Full-spectrum is safest vs. purified isolates of alkaloids. 
  • The form of Ashwagandha: For example, Gaia Herbs Ashwagandha Gummies have a higher dose per serving than our Ashwagandha Root. So be sure to check the labels.
  • Whether it’s a pure Ashwagandha supplement or one combined with other herbs: Superfood powders containing Ashwagandha and other herbs, for instance, may have less Ashwagandha per serving than a 100% Ashwagandha powder.
  • The person’s size, state of health, digestive health, and health goals.

Based on the daily range used in human studies, 250 - 600 mg daily is generally a good starting point.

For more details, check out: Ashwagandha Dosage—How to Take Ashwagandha Effectively.

Tips on When To Take Ashwagandha for Specific Health Concerns

As previously mentioned, in most human studies on Ashwagandha, the root extract was administered twice daily at approximately 120-300 mg per dose for a total of 240-600 mg total per day. REF#387 REF#388 REF#389 REF#390 REF#391 REF#392

Get the specifics on dosing in: Ashwagandha Dosage—How to Take Ashwagandha Effectively.

However, taking Ashwagandha twice daily is not for everyone.

If you have adrenal health issues, trouble sleeping, or low energy in the mornings, you may want to time your Ashwagandha differently.

Ashwagandha has been shown to support your adrenals in the normal production of cortisol (your body’s master stress hormone) via the HPA axis (Hypothalamus-Pituitary-Adrenal). REF#393

Therefore, taking Ashwagandha before bed may be helpful to promote relaxation and better quality sleep. REF#394 REF#395 REF#396

However, if you lack energy in the mornings, taking your Ashwagandha upon waking could offer support via your cortisol awakening response.*

The cortisol awakening response refers to naturally higher levels of cortisol a healthy person should produce after a sustained period of rest. REF#397

This is related to the hypothalamus-pituitary-adrenal (HPA) axis, which controls cortisol secretion within the sleep cycle and your stress response. REF#398

So, when should you take Ashwagandha for the best results?

It depends on your health concerns and goals.

However, it may be worth trying a larger dose right before bed if you have trouble sleeping at night.

If you struggle with energy dips in the morning, try taking a smaller dose when you wake up.

If you’re taking Ashwagandha for general physical, mental, and emotional well-being, hormone, or stress support, it probably makes sense to divide the dose.*

Many people also wonder when to take Ashwagandha to support post-workout recovery.

A systematic review of 12 studies published in the Journal of Function Morphology and Kinesiology also found Ashwagandha more effective than placebo for supporting strength and power, cardiorespiratory fitness, and fatigue/recovery in healthy men and women. REF#399


Study participants took between 120 mg and 1,250 mg daily of 100% Ashwagandha root extract, not necessarily after their workouts.

Therefore, taking Ashwagandha right before or after exercise does not appear necessary to experience its benefits. Per the studies, you can take it any time.

Gaia Herbs Adaptogen Performance Mushrooms & Herbs combines Ashwagandha with other energy, endurance, and adrenal-supportive herbs, making it a popular choice for athletes and exercise enthusiasts.*

How Long Does it Take to See Results From Ashwagandha?

Monitoring your results is key when determining the best time of day to take Ashwagandha.

As you track your progress, remember that herbs, including Ashwagandha, typically take time to work. 

How long? It depends on many factors, and different people report very different experiences. 

For example, many people feel immediate relaxation and desire to rest from taking Ashwagandha before bed.*

However, most of the studies referenced in this article lasted at least eight weeks. 

Remain consistent and talk to your practitioner about adjusting your timing or dosage if you aren’t getting results within a few weeks to a couple of months.*

A Few Helpful Tips on Taking Ashwagandha Consistently

With what you’ve learned in this article, you’re ready to start experimenting with the best time to take Ashwagandha or work with your practitioner to determine the best course of action.

Here are a few helpful tips for taking Ashwagandha consistently:

  • Consider capsules or a tincture to save time during the morning crunch. 
  • Everyday Adaptogen® is fantastic for blending into smoothies or shakes. It combines Ashwagandha with complementary herbs such as Maca, Cordyceps, Rhodiola, Shitake, and Schisandra, making it an excellent choice for athletes or anyone needing quick energy support.*
  • For a higher dose of full-spectrum Ashwagandha, consider Ashwagandha Gummies, with 6 grams of Ashwagandha per fruit-sweetened serving.
  • Gaia Herbs Golden Milk is a tasty and soothing way to enjoy an evening dose of Ashwagandha as you settle in for the night.
  • SleepThru® or Sleep Gummies are perfect for keeping on your nightstand to take just before bed.*

Want to Learn More about Ashwagandha’s Many Potential Health Benefits?

We have an extensive library of information to help you on your journey to greater well-being.

Check out the following for more information on Ashwagandha:

REFERENCES:

  • 1. Gustavo F. Gonzales, "Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands", Journal List Evid Based Complement Alternat Med v.2012; 2012 PMC3184420. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184420/
  • 2. Luis G Valerio Jr, Gustavo F Gonzales, "Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis", Toxicol Rev . 2005;24(1):11-35. doi: 10.2165/00139709-200524010-00002. PMID: 16042502. https://pubmed.ncbi.nlm.nih.gov/16042502/
  • 3. H. O. Meissner,1 P. Mrozikiewicz,2 T. Bobkiewicz-Kozlowska,3 A. Mscisz,2 B. Kedzia,2 A. Lowicka,2 H. Reich-Bilinska,4 W. Kapczynski,5 and I. Barchia6, "Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (I) Biochemical and Pharmacodynamic Study on Maca using Clinical Laboratory Model on Ovariectomized Rats", Journal List Int J Biomed Sci v.2(3); 2006 Sep PMC3614604. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614604/
  • 4. Eva Fries 1, Lucia Dettenborn, Clemens Kirschbaum, "The cortisol awakening response (CAR): facts and future directions", Int J Psychophysiol. 2009 Apr;72(1):67-73. doi: 10.1016/j.ijpsycho.2008.03.014.Epub 2008 Sep 30.. https://pubmed.ncbi.nlm.nih.gov/18854200/
  • 5. Nicolas C. Nicolaides 1, Alexandros N. Vgontzas 2, Ilia Kritikou 3, George Chrousos 4 Kenneth R Feingold 1, Bradley Anawalt 2, Alison Boyce 3, George Chrousos 4, Wouter W de Herder 5, Ketan Dhatariya 6, Kathleen Dungan 7, Jerome M Hershman 8, Johannes Hofland 9, Sanjay Kalra 10, Gregory Kaltsas 11, Christian Koch 12, Peter Kopp 13, Márta Korbonits 14, Christopher S Kovacs 15, Wendy Kuohung 16, Blandine Laferrère 17, Miles Levy 18, Elizabeth A McGee 19, Robert McLachlan 20, John E Morley 21, Maria New 22, Jonathan Purnell 23, Rakesh Sahay 24, Frederick Singer 25, Mark A Sperling 26, Constantine A Stratakis 27, Dace L Trence 28, Don P Wilson 29 , editors., "HPA Axis and Sleep", PMID: 25905298 Bookshelf ID: NBK279071. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 6. José Manuel Lozano Sánchez', Zoraida Axtle Serranol*, Julio Avilés Durán, Héctor Salvador Godoy Morales, Paola Berenice Merchand Álvarez, Ricardo Mera Mejía? Luis Felipe Montaño Estrada and Erika Patricia Rendón Huerta, "Peruvian Maca and Possible Impact on Fertility", Journal of Nutritional Health & Food Engineering. https://www.researchgate.net/profile/Jose-Manuel-Lozano-Sanchez/publication/317569911_Peruvian_Maca_and_Possible_Impact_on_Fertility/links/59494b03aca272a30c6cae11/Peruvian-Maca-and-Possible-Impact-on-Fertility.pdf
  • 7. A López-Fando 1, M P Gómez-Serranillos, I Iglesias, O Lock, U P Upamayta, M E Carretero, "Lepidium peruvianum chacon restores homeostasis impaired by restraint stress", Phytother Res . 2004 Jun;18(6):471-4. doi: 10.1002/ptr.1455.. https://pubmed.ncbi.nlm.nih.gov/15287072/
  • 8. Gustavo F. Gonzales *, "Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands", Evid Based Complement Alternat Med. 2012; 2012: 193496. Published online 2011 Oct 2. doi: 10.1155/2012/193496. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184420/
  • 9. José Manuel Lozano Sánchez', Zoraida Axtle Serranol*, Julio Avilés Durán, Héctor Salvador Godoy Morales, Paola Berenice Merchand Álvarez, Ricardo Mera Mejía? Luis Felipe Montaño Estrada and Erika Patricia Rendón Huerta, "Peruvian Maca and Possible Impact on Fertility", Journal of Nutritional Health & Food Engineering. https://www.researchgate.net/profile/Jose-Manuel-Lozano-Sanchez/publication/317569911_Peruvian_Maca_and_Possible_Impact_on_Fertility/links/59494b03aca272a30c6cae11/Peruvian-Maca-and-Possible-Impact-on-Fertility.pdf
  • 10. Maria Rosales-Hartshorn*, "Maca: Botanical Medicine from the Andes", Volume 1 : Issue 2 Article Ref. #: 1000AFTNSOJ1e001. https://www.openventio.org/Volume1-Issue2/Maca-Botanical-Medicine-from-the-Andes-AFTNSOJ-1-e001.pdf
  • 11. Natália da Silva Leitão Peres 1, Letícia Cabrera Parra Bortoluzzi, Leila Larisa Medeiros Marques, Maysa Formigoni, Renata Hernandez Barros Fuchs, Adriana Aparecida Droval, Flávia Aparecida Reitz Cardoso, "Medicinal effects of Peruvian maca (Lepidium meyenii): a review", Food Funct. 2020 Jan 29;11(1):83-92. doi: 10.1039/c9fo02732g.. https://pubmed.ncbi.nlm.nih.gov/31951246/
  • 12. Office of Communications, "How common is infertility?", Home- Health- A to Z List- Infertility and Fertility- About- How common is infertility?. https://www.nichd.nih.gov/health/topics/infertility/conditioninfo/common#f1
  • 13. ASRM, American Society for Reproductive Medicine., "In approximately 40 percent of infertile couples, the male partner is either the sole cause or a contributing cause of infertility", Home Infographic Gallery. https://www.reproductivefacts.org/resources/infographic-gallery/images/in-approximately-40-percent-of-infertile-couples-the-male-partner-is-either-the-sole-cause-or-a-contributing-cause-of-infertility/
  • 14. G F Gonzales 1, A Cordova, C Gonzales, A Chung, K Vega, A Villena, "Lepidium meyenii (Maca) improved semen parameters in adult men", Asian J Androl. 2001 Dec;3(4):301-3.. https://pubmed.ncbi.nlm.nih.gov/11753476/
  • 15. José Manuel Lozano Sánchez', Zoraida Axtle Serranol*, Julio Avilés Durán, Héctor Salvador Godoy Morales, Paola Berenice Merchand Álvarez, Ricardo Mera Mejía? Luis Felipe Montaño Estrada and Erika Patricia Rendón Huerta, "Peruvian Maca and Possible Impact on Fertility", DOI:10.15406/jnhfe.2017.06.00217. https://www.researchgate.net/publication/317569911_Peruvian_Maca_and_Possible_Impact_on_Fertility
  • 16. Daniel Nedresky; Gurdeep Singh., "Physiology, Luteinizing Hormone", Treasure Island (FL): StatPearls Publishing; 2022 Jan-.. https://www.ncbi.nlm.nih.gov/books/NBK539692/
  • 17. G F Gonzales 1, A Cordova, C Gonzales, A Chung, K Vega, A Villena, "Lepidium meyenii (Maca) improved semen parameters in adult men", Asian J Androl. 2001 Dec;3(4):301-3.. https://pubmed.ncbi.nlm.nih.gov/11753476/
  • 18. G F Gonzales, M Gasco, A Córdova, A Chung, J Rubio and L Villegas, "Effect of Lepidium meyenii (Maca) on spermatogenesis in male rats acutely exposed to high altitude (4340 m)", Instituto de Investigaciones de la Altura, and Departamento de Ciencias Biolo´gicas y Fisiolo´gicas Facultad de Ciencas y Filosofı´a, Universidad Peruana Cayetano Heredia, PO Box 1843, Lima, Peru (Requests for offprints should be addressed to G F Gonzales, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PO Box 1843, Lima, Peru; Email: iiad@upch.edu.pe). http://eplant.njau.edu.cn/maca/publication/Effect%20of%20Lepidium%20meyenii%20(Maca)%20on%20spermatogenesis%20in%20male%20rats%20acutely%20exposed%20to%20high%20altitude%20(4340%20m).pdf
  • 19. A López-Fando, M P Gómez-Serranillos, I Iglesias, O Lock, U P Upamayta, M E Carretero, "Lepidium peruvianum chacon restores homeostasis impaired by restraint stress", Phytother Res . 2004 Jun;18(6):471-4. doi: 10.1002/ptr.1455.. https://pubmed.ncbi.nlm.nih.gov/15287072/
  • 20. G. F. Gonzales,A. Córdova,K. Vega,A. Chung,A. Villena,C. Góñez,S. Castillo, "Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men", Journal of Andrology. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1439-0272.2002.00519.x
  • 21. Byung-Cheul Shin, Myeong Soo Lee, Eun Jin Yang, Hyun-Suk Lim, Edzard Ernst, "Maca (L. meyenii) for improving sexual function: a systematic review", BMC Complement Altern Med . 2010 Aug 6;10:44. doi: 10.1186/1472-6882-10-44.. https://pubmed.ncbi.nlm.nih.gov/20691074/
  • 22. José Manuel Lozano Sánchez, Zoraida Axtle, Julio Aviles, Héctor Salvador Godoy Morales, Paola Berenice Merchand Álvarez, Ricardo Mera Mejía, Luis Felipe Montaño Estrada, Erika Patricia Rendón Huerta, "Peruvian Maca and Possible Impact on Fertility", Journal of Nutritional Health & Food Engineering. https://www.researchgate.net/publication/317569911_Peruvian_Maca_and_Possible_Impact_on_Fertility
  • 23. Hongkang Zhu, Wenqian Xu, Ning Wang, Wenhao Jiang, Yuliang Cheng, Yahui Guo, Weirong Yao, Bin Hu, Peng Du and He Qian, "Anti-fatigue effect of Lepidium meyenii Walp. (Maca) on preventing mitochondria-mediated muscle damage and oxidative stress in vivo and vitro†", Journal of Food & Function. https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo00383f/unauth
  • 24. Mark Stone, Alvin Ibarra, Marc Roller, Andrea Zangara, Emma Stevenson, "A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen", J Ethnopharmacol . 2009 Dec 10;126(3):574-6. doi: 10.1016/j.jep.2009.09.012. Epub 2009 Sep 23.. https://pubmed.ncbi.nlm.nih.gov/19781622/
  • 25. Gustavo F Gonzales, Sara Miranda, Jessica Nieto, Gilma Fernández, Sandra Yucra, Julio Rubio, Pedro Yi & Manuel Gasco, "Red maca (Lepidium meyenii) reduced prostate size in rats", Reprod Biol Endocrinol 3, 5 (2005). https://doi.org/10.1186/1477-7827-3-5. https://rbej.biomedcentral.com/articles/10.1186/1477-7827-3-5
  • 26. C Gonzales, J Leiva-Revilla, J Rubio, M Gasco, G F Gonzales, "Effect of red maca (Lepidium meyenii) on prostate zinc levels in rats with testosterone-induced prostatic hyperplasia", Andrologia . 2012 May;44 Suppl 1:362-9. doi: 10.1111/j.1439-0272.2011.01190.x. Epub 2011 Jul 18.. https://pubmed.ncbi.nlm.nih.gov/21762188/
  • 27. G. F. Gonzales,A. Córdova,K. Vega,A. Chung,A. Villena,C. Góñez,S. Castillo, "Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men", Journal of Andrology. https://onlinelibrary.wiley.com/doi/full/10.1046/j.1439-0272.2002.00519.x
  • 28. Y Ohta, N Kawate, T Inaba, H Morii, K Takahashi, H Tamada, "Feeding hydroalcoholic extract powder of Lepidium meyenii (maca) enhances testicular gene expression of 3β-hydroxysteroid dehydrogenase in rats", Andrologia . 2017 Dec;49(10). doi: 10.1111/and.12792. Epub 2017 Mar 6.. https://pubmed.ncbi.nlm.nih.gov/28261840/
  • 29. Ángel Rodríguez-Huamán, Sandra Casimiro-Gonzales, Jorge Antonio Chávez-Pérez, Carla Gonzales-Arimborgo, Richard Cisneros-Fernández, Luis Ángel Aguilar-Mendoza, Gustavo F Gonzales, "Antioxidant and neuroprotector effect of Lepidium meyenii (maca) methanol leaf extract against 6-hydroxy dopamine (6-OHDA)-induced toxicity in PC12 cells", Toxicol Mech Methods . 2017 May;27(4):279-285. doi: 10.1080/15376516.2016.1275908. Epub 2017 Jan 8.. https://pubmed.ncbi.nlm.nih.gov/28007001/
  • 30. Bárbara Teixeira, António Marques, Cristina Ramos, Maria Carmo Serrano, Olívia Matos, Nuno R Neng, José Nogueira, Jorge M. A. Saraiva, Maria Leonor Nunes, "Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil", Journal of the Science of Food and Agriculture 93(11) DOI:10.1002/jsfa.6089. https://www.researchgate.net/publication/236104725_Chemical_composition_and_bioactivity_of_different_oregano_Origanum_vulgare_extracts_and_essential_oil
  • 31. Wesam Kooti, Zahra Hasanzadeh-Noohi, Naim Sharafi-Ahvazi, Majid Asadi-Samani, Damoon Ashtary-Larky, "Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa)", Chin J Nat Med . 2016 Oct;14(10):732-745. doi: 10.1016/S1875-5364(16)30088-7. Epub 2016 Oct 31.. https://pubmed.ncbi.nlm.nih.gov/28236403/
  • 32. Łukasz Łuczaj & Wojciech M Szymański, "Wild vascular plants gathered for consumption in the Polish countryside: a review.", Journal of Ethnobiology and Ethnomedicine volume 3, Article number: 17 (2007). https://ethnobiomed.biomedcentral.com/articles/10.1186/1746-4269-3-17
  • 33. IKHLAS A. KHAN, EHAB A. ABOURASHED, "Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics.", John Wiley & Sons, Inc., Hoboken, New Jersey. https://naturalingredient.org/wp/wp-content/uploads/leungs-encyclopedia-of-common-natural-ingredients-3rd-edition.pdf
  • 34. Adom MB, Taher M, Mutalabisin MF, Amri MS, Abdul Kudos MB, Wan Sulaiman MWA, Sengupta P, Susanti D, "Chemical constituents and medical benefits of Plantago major.", Biomedecine & Pharmacotherapie, 10 Oct 2017, 96:348-360 DOI: 10.1016/j.biopha.2017.09.152 PMID: 29028587. https://europepmc.org/article/med/29028587#similar-articles
  • 35. ZOT Organic, "What is Licorice?", General Info. https://zotorganic.com/information/licorice/#:~:text=The%20plant%20is%20prized%20for,shrub%2C%20is%20officially%20a%20weed.
  • 36. Dalia Akramiene, Anatolijus Kondrotas, Janina Didziapetriene, Egidijus Kevelaitis, "Effects of beta-glucans on the immune system", Medicina (Kaunas) . 2007;43(8):597-606.. https://pubmed.ncbi.nlm.nih.gov/17895634/
  • 37. R C Rosen, "Prevalence and risk factors of sexual dysfunction in men and women", Curr Psychiatry Rep . 2000 Jun;2(3):189-95. doi: 10.1007/s11920-996-0006-2.. https://pubmed.ncbi.nlm.nih.gov/11122954/
  • 38. Natália da Silva Leitão Peres, Letícia Cabrera Parra Bortoluzzi, Leila Larisa Medeiros Marques, Maysa Formigoni, Renata Hernandez Barros Fuchs, Adriana Aparecida Droval, Flávia Aparecida Reitz Cardoso, "Medicinal effects of Peruvian maca (Lepidium meyenii): a review", Food Funct . 2020 Jan 29;11(1):83-92. doi: 10.1039/c9fo02732g.. https://pubmed.ncbi.nlm.nih.gov/31951246/
  • 39. Nicole A Brooks, Gisela Wilcox, Karen Z Walker, John F Ashton, Marc B Cox, Lily Stojanovska, "Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content", Menopause . 2008 Nov-Dec;15(6):1157-62. doi: 10.1097/gme.0b013e3181732953.. https://pubmed.ncbi.nlm.nih.gov/18784609/
  • 40. Maria Rosales-Hartshorn*, "Maca: Botanical Medicine from the Andes", Adv Food Technol Nutr Sci Open J. 2015; 1(2): e1-e6. doi: 10.17140/AFTNSOJ-1-e001. https://www.openventio.org/Volume1-Issue2/Maca-Botanical-Medicine-from-the-Andes-AFTNSOJ-1-e001.pdf
  • 41. Sánchez JML, Serrano ZA, Durán JA, Morales HSG, Álvarez PBM (2017), "Peruvian Maca and Possible Impact on Fertility", J Nutr Health Food Eng 6(5): 00217. DOI: 10.15406/jnhfe.2017.06.00217. https://www.researchgate.net/profile/Jose-Manuel-Lozano-Sanchez/publication/317569911_Peruvian_Maca_and_Possible_Impact_on_Fertility/links/59494b03aca272a30c6cae11/Peruvian-Maca-and-Possible-Impact-on-Fertility.pdf
  • 42. Leila Mazaheri Nia, Mina Iravani, Parvin Abedi, Bahman Cheraghian, "Effect of Zinc on Testosterone Levels and Sexual Function of Postmenopausal Women: A Randomized Controlled Trial", J Sex Marital Ther . 2021;47(8):804-813. doi: 10.1080/0092623X.2021.1957732. Epub 2021 Jul 27.. https://pubmed.ncbi.nlm.nih.gov/34311679/
  • 43. G. F. Gonzales,A. Córdova,K. Vega,A. Chung,A. Villena,C. Góñez,S. Castillo, "Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men", Journal of Andrology. https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1439-0272.2002.00519.x
  • 44. Byung-Cheul Shin 1, Myeong Soo Lee, Eun Jin Yang, Hyun-Suk Lim, Edzard Ernst, "Maca (L. meyenii) for improving sexual function: a systematic review", BMC Complement Altern Med . 2010 Aug 6;10:44. doi: 10.1186/1472-6882-10-44.. https://pubmed.ncbi.nlm.nih.gov/20691074/
  • 45. Ghanbarali Raeis Jalali, Jamshid Roozbeh, Azam Mohammadzadeh, Maryam Sharifian, Mohammad Mahdi Sagheb, Alireza Hamidian Jahromi, Sanaz Shabani, Fariborz Ghaffarpasand, Raha Afshariani, "Impact of oral zinc therapy on the level of sex hormones in male patients on hemodialysis", Ren Fail . 2010 May;32(4):417-9. doi: 10.3109/08860221003706958.. https://pubmed.ncbi.nlm.nih.gov/20446777/
  • 46. Tahoora Shomali, Mahnaz Taherianfard, Maryam Dalvand, Fatemeh Namazi, "Effect of pharmacological doses of niacin on testicular structure and function in normal and diabetic rats", Andrologia . 2018 Dec;50(10):e13142. doi: 10.1111/and.13142. Epub 2018 Sep 6.. https://pubmed.ncbi.nlm.nih.gov/30191583/
  • 47. Gonzales G. F., Cordova A., Gonzales C., Chung A., Vega K., Villena A., "Lepidium meyenii (Maca) improved semen parameters in adult men.", Asian Journal of Andrology. 2001;3(4):301–303.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411442/#B19
  • 48. Bogani P., Simonini F., Iriti M., et al., "Lepidium meyenii (Maca) does not exert direct androgenic activities.", Journal of Ethnopharmacology. 2006;104(3):415–417. doi: 10.1016/j.jep.2005.09.028.. ncbi.nlm.nih.gov/pmc/articles/PMC4411442/#B27
  • 49. Gonzalez G. F., Córdova A., Vega K., Chung A., Villena A., Góñez C., "Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing propeties, on serum reproductive hormone levels in adult healthy men.", Journal of Endocrinology. 2003;176(1):163–168. doi: 10.1677/joe.0.1760163.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411442/#B28
  • 50. Christina M. Dording , * Pamela J. Schettler, Elizabeth D. Dalton, Susannah R. Parkin, Rosemary S. W. Walker, Kara B. Fehling, Maurizio Fava, and David Mischoulon, "A Double-Blind Placebo-Controlled Trial of Maca Root as Treatment for Antidepressant-Induced Sexual Dysfunction in Women", Journal List Evid Based Complement Alternat Med v.2015; 2015 PMC4411442. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411442/
  • 51. Srikugan L., Sankaralingam A., McGowan B., "First case report of testosterone assay-interference in a female taking maca (Lepidium meyenii) BMJ Case Reports.", 2011 doi: 10.1136/bcr.01.2011.3781.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411442/#B26
  • 52. Olivia Remes,Carol Brayne,Rianne van der Linde,Louise Lafortune, "A systematic review of reviews on the prevalence of anxiety disorders in adult populations", Journal of Brain and Behavior, 05 June 2016. https://onlinelibrary.wiley.com/doi/10.1002/brb3.497
  • 53. Rohit Verma, Yatan Pal Singh Balhara, and Chandra Shekhar Gupta, "Gender differences in stress response: Role of developmental and biological determinants", Journal List Ind Psychiatry J v.20(1); Jan-Jun 2011 PMC3425245. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425245/
  • 54. Mohammad Hossein Mirjalili, Elisabeth Moyano, Mercedes Bonfill, Rosa M Cusido, Javier Palazón, "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine", Molecules . 2009 Jul 3;14(7):2373-93.. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 55. R C Rosen, "Prevalence and risk factors of sexual dysfunction in men and women", Curr Psychiatry Rep . 2000 Jun;2(3):189-95. DOI: 10.1007/s11920-996-0006-2.. https://pubmed.ncbi.nlm.nih.gov/11122954/
  • 56. Swati Dongre, Deepak Langade, Sauvik Bhattacharyya, "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study", Biomed Res Int . 2015;2015:284154. doi: 10.1155/2015/284154.. https://pubmed.ncbi.nlm.nih.gov/26504795/
  • 57. UT NEWS, "Stress Hormone Blocks Testosterone’s Effects, Study Shows", Journal of Science and Technology. https://news.utexas.edu/2010/09/27/stress-hormone-blocks-testosterones-effects-study-shows/
  • 58. Rashad, N.M., Samir, G.M., "Prevalence, risks, and comorbidity of thyroid dysfunction: a cross-sectional epidemiological study", Egypt J Intern Med 31, 635–641 (2019). https://ejim.springeropen.com/articles/10.4103/ejim.ejim_22_19
  • 59. Cleveland Clinic, "Thyroid: What It Is, Function and Problems", Journal of Body Systems & Organs. https://my.clevelandclinic.org/health/body/23188-thyroid
  • 60. Sharma AK, Basu I, Singh S., "Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial", J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. PMID: 28829155.. https://pubmed.ncbi.nlm.nih.gov/28829155/
  • 61. Chandrasekhar K, Kapoor J, Anishetty S., "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577.. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 62. Stephens MA, Wand G., "Stress and the HPA axis: role of glucocorticoids in alcohol dependence", Alcohol Res. 2012;34(4):468-83. PMID: 23584113; PMCID: PMC3860380.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860380/
  • 63. Centers for Disease Control and Prevention, "1 in 3 adults don’t get enough sleep", CDC.gov. https://www.cdc.gov/media/releases/2016/p0215-enough-sleep.html
  • 64. Centers for Disease Control and Prevention, "Sleep and Sleep Disorders", CDC.gov. https://www.cdc.gov/sleep/data_statistics.html
  • 65. Krishnan V, Collop NA., "Gender differences in sleep disorders", Curr Opin Pulm Med. 2006 Nov;12(6):383-9. doi: 10.1097/01.mcp.0000245705.69440.6a. PMID: 17053485.. https://pubmed.ncbi.nlm.nih.gov/17053485/
  • 66. Danielle Pacheco, Ealena Callender, "Women and Sleep", Sleep Foundation. https://www.sleepfoundation.org/women-sleep
  • 67. Langade D, Thakare V, Kanchi S, Kelgane S., "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17. PMID: 32818573.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 68. Abhijit Deshpande, Nushafreen Irani, Ratna Balkrishnan, Irin Rosanna Benny, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Medicine, Volume 72, 2020, Pages 28-36, ISSN 1389-9457,. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 69. Mahesh K. Kaushik, Sunil C. Kaul, Renu Wadhwa, Masashi Yanagisawa, Yoshihiro Urade, "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", plos.org DOI:10.1371/journal.pone.0172508. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508#abstract0
  • 70. Auddy B, Hazra J, Mitra A, et al., "A standardized Withania Somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study", J Am Neutraceut Assoc 2008;11:50–6.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 71. Andrade C, Aswath A, Chaturvedi SK, et al., "A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera", Indian J Psychiatry 2000;42:295–301.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R18
  • 72. Fries E, Dettenborn L, Kirschbaum C., "The cortisol awakening response (CAR): facts and future directions", Int J Psychophysiol. 2009 Apr;72(1):67-73. doi: 10.1016/j.ijpsycho.2008.03.014. Epub 2008 Sep 30. PMID: 18854200.. https://pubmed.ncbi.nlm.nih.gov/18854200/
  • 73. Nicolas C. Nicolaides, Alexandros N. Vgontzas, Ilia Kritikou, George Chrousos Kenneth R Feingold, Bradley Anawalt, Alison Boyce, George Chrousos, Wouter W de Herder, Ketan Dhatariya, Kathleen Dungan, Jerome M Hershman, Johannes Hofland, Sanjay Kalra, Gregory Kaltsas, Christian Koch, Peter Kopp, Márta Korbonits, Christopher S Kovacs, Wendy Kuohung, Blandine Laferrère, Miles Levy, Elizabeth A McGee, Robert McLachlan, John E Morley, Maria New, Jonathan Purnell, Rakesh Sahay, Frederick Singer, Mark A Sperling, Constantine A Stratakis, Dace L Trence, Don P Wilson, "HPA Axis and Sleep", In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. 2020 Nov 24. PMID: 25905298 Bookshelf ID: NBK279071. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 74. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S., "Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study", Phytomedicine. 2000 Dec;7(6):463-9. doi: 10.1016/S0944-7113(00)80030-6. PMID: 11194174.. https://pubmed.ncbi.nlm.nih.gov/11194174/
  • 75. Gopal S, Ajgaonkar A, Kanchi P, Kaundinya A, Thakare V, Chauhan S, Langade D., "Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study", J Obstet Gynaecol Res. 2021 Dec;47(12):4414-4425. doi: 10.1111/jog.15030. Epub 2021 Sep 22. PMID: 34553463.. https://pubmed.ncbi.nlm.nih.gov/34553463/
  • 76. Chandrasekhar K, Kapoor J, Anishetty S., "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577.. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 77. Khedgikar V, Kushwaha P, Gautam J, Verma A, Changkija B, Kumar A, Sharma S, Nagar GK, Singh D, Trivedi PK, Sangwan NS, Mishra PR, Trivedi R., "Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone", Cell Death Dis. 2013 Aug 22;4(8):e778. doi: 10.1038/cddis.2013.294. PMID: 23969857; PMCID: PMC3763455.. https://pubmed.ncbi.nlm.nih.gov/23969857/
  • 78. Sandi C., "Stress and cognition", Wiley Interdiscip Rev Cogn Sci. 2013 May;4(3):245-261. doi: 10.1002/wcs.1222. Epub 2013 Jan 22. PMID: 26304203.. https://pubmed.ncbi.nlm.nih.gov/26304203/
  • 79. Killgore WD., "Effects of sleep deprivation on cognition", Prog Brain Res. 2010;185:105-29. doi: 10.1016/B978-0-444-53702-7.00007-5. PMID: 21075236.. https://pubmed.ncbi.nlm.nih.gov/21075236/
  • 80. Ali SA, Begum T, Reza F., "Hormonal Influences on Cognitive Function", Malays J Med Sci. 2018 Jul;25(4):31-41. doi: 10.21315/mjms2018.25.4.3. Epub 2018 Aug 30. PMID: 30914845; PMCID: PMC6422548.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422548/
  • 81. Choudhary D, Bhattacharyya S, Bose S., "Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions", J Diet Suppl. 2017 Nov 2;14(6):599-612. doi: 10.1080/19390211.2017.1284970. Epub 2017 Feb 21. PMID: 28471731.. https://pubmed.ncbi.nlm.nih.gov/28471731/
  • 82. Dar NJ, MuzamilAhmad., "Neurodegenerative diseases and Withania somnifera (L.): An update.", J Ethnopharmacol. 2020 Jun 28;256:112769. doi: 10.1016/j.jep.2020.112769. Epub 2020 Mar 30. PMID: 32240781.. https://pubmed.ncbi.nlm.nih.gov/32240781/
  • 83. Bonilla DA, Moreno Y, Gho C, Petro JL, Odriozola-Martínez A, Kreider RB., "Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis", J Funct Morphol Kinesiol. 2021 Feb 11;6(1):20. doi: 10.3390/jfmk6010020. PMID: 33670194; PMCID: PMC8006238.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006238/
  • 84. GRAHAM BINDER, "Researchers with the College of AGNR study nutrient-packed microgreens", College of Agriculture & Natural Resources, September 6, 2012. https://agnr.umd.edu/news/mighty-microgreens
  • 85. GAO, "While Levels in Clothing Generally Appear to Be Low, Allergic Contact Dermatitis Is a Health Issue for Some People", United States Government Accountability Office, Report to Congressional Committees, August 2010. https://www.gao.gov/assets/gao-10-875.pdf
  • 86. Dongre S, Langade D, Bhattacharyya S., "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study.", Biomed Res Int. 2015;2015:284154. doi: 10.1155/2015/284154. Epub 2015 Oct 4. PMID: 26504795; PMCID: PMC4609357.. https://pubmed.ncbi.nlm.nih.gov/26504795/
  • 87. Chauhan, S, Srivastava, MK, Pathak, AK., "Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: a randomized controlled trial", Health Sci Rep. 2022; 5:e741. doi:10.1002/hsr2.741. https://onlinelibrary.wiley.com/doi/10.1002/hsr2.741
  • 88. Langade D, Thakare V, Kanchi S, Kelgane S., "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17. PMID: 32818573.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 89. Abhijit Deshpande, Nushafreen Irani, Ratna Balkrishnan, Irin Rosanna Benny,, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults,", Sleep Medicine, Volume 72, 2020, Pages 28-36, ISSN 1389-9457, https://doi.org/10.1016/j.sleep.2020.03.012.. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 90. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S, "Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study", Phytomedicine. 2000 Dec;7(6):463-9. doi: 10.1016/S0944-7113(00)80030-6. PMID: 11194174.. https://pubmed.ncbi.nlm.nih.gov/11194174/
  • 91. Rashad, N.M., Samir, G.M., "Prevalence, risks, and comorbidity of thyroid dysfunction: a cross-sectional epidemiological study", Egypt J Intern Med 31, 635–641 (2019). https://doi.org/10.4103/ejim.ejim_22_19. https://ejim.springeropen.com/articles/10.4103/ejim.ejim_22_19
  • 92. Durg S, Bavage S, Shivaram SB, "Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application", Phytother Res. 2020 May;34(5):1041-1059. doi: 10.1002/ptr.6589. Epub 2020 Jan 23. PMID: 31975514.. https://pubmed.ncbi.nlm.nih.gov/31975514/
  • 93. ASRM, American Society for Reproductive Medicine, "In approximately 40 percent of infertile couples, the male partner is either the sole cause or a contributing cause of infertility", Reproductivefacts.org/resources/infographic-gallery. https://www.reproductivefacts.org/resources/infographic-gallery/images/in-approximately-40-percent-of-infertile-couples-the-male-partner-is-either-the-sole-cause-or-a-contributing-cause-of-infertility/
  • 94. Tiwari S, Gupta SK, Pathak AK, "A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults", J Ethnopharmacol. 2021 May 23;272:113929. doi: 10.1016/j.jep.2021.113929. Epub 2021 Feb 15. PMID: 33600918.. https://pubmed.ncbi.nlm.nih.gov/33600918/
  • 95. Chandrasekhar K, Kapoor J, Anishetty S, "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022. PMID: 23439798; PMCID: PMC3573577. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 96. Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J, "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine", Molecules. 2009 Jul 3;14(7):2373-93. doi: 10.3390/molecules14072373. PMID: 19633611; PMCID: PMC6255378. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 97. Carnegie Mellon University, "Stress Contributes To Range Of Chronic Diseases, Review Shows", ScienceDaily. ScienceDaily, 10 October 2007. https://www.sciencedaily.com/releases/2007/10/071009164122.htm
  • 98. Bremner JD, "Does stress damage the brain?", Biol Psychiatry. 1999 Apr 1;45(7):797-805. doi: 10.1016/s0006-3223(99)00009-8. PMID: 10202566. https://pubmed.ncbi.nlm.nih.gov/10202566/
  • 99. Kalmbach DA, Anderson JR, Drake CL, "The impact of stress on sleep: Pathogenic sleep reactivity as a vulnerability to insomnia and circadian disorders", J Sleep Res. 2018 Dec;27(6):e12710. doi: 10.1111/jsr.12710. Epub 2018 May 24. PMID: 29797753; PMCID: PMC7045300. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045300/
  • 100. National Institutes of Health, "Poor Sleep Linked With Higher Blood Sugar", newsinhealth.nih.gov/Health Capsule/ July 2022. https://newsinhealth.nih.gov/2020/07/poor-sleep-linked-higher-blood-sugar
  • 101. Winston D, Maimes S, "Adaptogens: Herbs for Strength, Stamina, and Stress Relief", Rochester: Inner Traditions/Bear & Co. Vol. 48. Rochester: Inner Traditions/Bear & Co; 2007; p. 53. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/#REF8
  • 102. Bhatnagar M, Sharma D, Salvi M, "Neuroprotective effects of Withania somnifera dunal.: A possible mechanism", Neurochem Res. 2009 Nov;34(11):1975-83. doi: 10.1007/s11064-009-9987-7. Epub 2009 May 15. PMID: 19444606. https://pubmed.ncbi.nlm.nih.gov/19444606/
  • 103. Salve J, Pate S, Debnath K, Langade D, "Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study", Cureus. 2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466. PMID: 32021735; PMCID: PMC6979308. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/
  • 104. Gopukumar, K.Thanawala, S. Somepalli, V. Rao Sathyanaryana, T. S. Thamatam, V.B. Chauhan, S., "Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study", Evidence-Based Complementary and Alternative Medicine/ Volume 2021/Article ID 8254344. https://www.hindawi.com/journals/ecam/2021/8254344/
  • 105. Choudhary D, Bhattacharyya S, Bose S., "Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions", J Diet Suppl. 2017 Nov 2;14(6):599-612. doi: 10.1080/19390211.2017.1284970. Epub 2017 Feb 21. PMID: 28471731. https://pubmed.ncbi.nlm.nih.gov/28471731/
  • 106. Dar NJ, MuzamilAhmad, "Neurodegenerative diseases and Withania somnifera (L.): An update", J Ethnopharmacol. 2020 Jun 28;256:112769. doi: 10.1016/j.jep.2020.112769. Epub 2020 Mar 30. PMID: 32240781. https://pubmed.ncbi.nlm.nih.gov/32240781/
  • 107. LULU XIE, HONGYI KANG, QIWU XU, MICHAEL J. CHEN, YONGHONG LIAO, MEENAKSHISUNDARAM THIYAGARAJAN, JOHN O’DONNELL, DANIEL J. CHRISTENSEN, CHARLES NICHOLSON, JEFFREY J. ILIFF, TAKAHIRO TAKANO, RASHID DEANE, AND MAIKEN NEDERGAARD, "Sleep Drives Metabolite Clearance from the Adult Brain", SCIENCE 18 Oct 2013 Vol 342, Issue 6156 pp. 373-377 DOI: 10.1126/science.1241224. https://www.science.org/doi/10.1126/science.1241224
  • 108. Bhatnagar M, Sharma D, Salvi M, "Neuroprotective effects of Withania somnifera dunal.: A possible mechanism", Neurochem Res. 2009 Nov;34(11):1975-83. doi: 10.1007/s11064-009-9987-7. Epub 2009 May 15. PMID: 19444606. https://pubmed.ncbi.nlm.nih.gov/19444606/
  • 109. Baker C, Kirby JB, O'Connor J, Lindsay KG, Hutchins A, Harris M, "The Perceived Impact of Ashwagandha on Stress, Sleep Quality, Energy, and Mental Clarity for College Students: Qualitative Analysis of a Double-Blind Randomized Control Trial", J Med Food. 2022 Aug 18. doi: 10.1089/jmf.2022.0042. Epub ahead of print. PMID: 35984870. https://pubmed.ncbi.nlm.nih.gov/35984870/
  • 110. Nayely Leyva-López, et al, "Essential Oils of Oregano: Biological Activity beyond Their Antimicrobial Properties", https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152729/
  • 111. S. Santoya et al, "Supercritical carbon dioxide extraction of compounds with antimicrobial activity from Origanum vulgare L.: determination of optimal extraction parameters", https://pubmed.ncbi.nlm.nih.gov/16496578/
  • 112. Snigdha Sacena et al, "Evaluation of Systemic Oxidative Stress in Patients with Premature Canities and Correlation of Severity of Hair Graying with the Degree of Redox Imbalance", https://pubmed.ncbi.nlm.nih.gov/32549695/
  • 113. Yunes Panahi et al, "Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial", https://pubmed.ncbi.nlm.nih.gov/25842469/
  • 114. Stephen C Barker & Phillip M Altman, "An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application - melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a "suffocation" pediculicide", https://bmcdermatol.biomedcentral.com/articles/10.1186/1471-5945-11-14
  • 115. C Hay et al, "Randomized trial of aromatherapy. Successful treatment for alopecia areata", https://pubmed.ncbi.nlm.nih.gov/9828867/
  • 116. "Synaptic Pruning", https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/synaptic-pruning
  • 117. CeJpeK, K, "“Antioxidant Activity in Variously Prepared Elderberry Foods and Supplements.”", Czech J. Food Sci. Vol. 27, 2009, Special Issue. https://www.agriculturejournals.cz/publicFiles/07578.pdf
  • 118. Porter RS, Bode RF, "A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products", Phytother Res. 2017 Apr;31(4):533-554. doi: 10.1002/ptr.5782. Epub 2017 Feb 15. PMID: 28198157..
  • 119. Deepak Langade, Subodh Kanchi, Jaising Salve, Khokan Debnath, and Dhruv Ambegaokar, "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study", Cureus. 2019 Sep; 11(9): e5797. Published online 2019 Sep 28. doi: 10.7759/cureus.5797 PMCID: PMC6827862PMID: 31728244. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827862/
  • 120. Mohammad Hossein Mirjalili, Elisabeth Moyano, Mercedes Bonfill, Rosa M Cusido, Javier Palazón, "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine", Molecules. 2009 Jul 3;14(7):2373-93. doi: 10.3390/molecules14072373.. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 121. Deepak Langade, Subodh Kanchi, Jaising Salve, Khokan Debnath, Dhruv Ambegaokar, "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study", Cureus . 2019 Sep 28;11(9):e5797. doi: 10.7759/cureus.5797.. https://pubmed.ncbi.nlm.nih.gov/31728244/
  • 122. Biswajit Auddy, PhD1; Jayaram Hazra, PhD2; Achintya Mitra, MD2; Bruce Abedon, PhD3; Shibnath Ghosal, PhD1, "A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study", JANA Vol 11, No.1 2008. https://blog.priceplow.com/wp-content/uploads/2014/08/withania_review.pdf
  • 123. K Chandrasekhar, Jyoti Kapoor, Sridhar Anishetty, "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022.. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 124. Deepak Langade, Vaishali Thakare, Subodh Kanchi, Sunil Kelgane, "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", Randomized Controlled Trial J Ethnopharmacol. 2021 Jan 10;264:113276.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 125. Abhijit Deshpandea, Nushafreen Irania, Ratna BalkrishnanaIrin, Rosanna Bennyb, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Medicine Volume 72, August 2020, Pages 28-36. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 126. Mahesh K. Kaushik ,Sunil C. Kaul, Renu Wadhwa,Masashi Yanagisawa, Yoshihiro Urade, "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172508. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508
  • 127. Mahesh K. Kaushik ,Sunil C. Kaul, Renu Wadhwa,Masashi Yanagisawa, Yoshihiro Urade, "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172508. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508
  • 128. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Medicine (Baltimore). 2019 Sep; 98(37): e17186. Published online 2019 Sep 13. doi: 10.1097/MD.0000000000017186. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 129. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Medicine (Baltimore). 2019 Sep; 98(37): e17186. Published online 2019 Sep 13. doi: 10.1097/MD.0000000000017186. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R18
  • 130. Nicolas C. Nicolaides, Alexandros N. Vgontzas, Ilia Kritikou, George Chrousos Kenneth R Feingold, Bradley Anawalt, Alison Boyce, George Chrousos, Wouter W de Herder, Ketan Dhatariya, Kathleen Dungan, Jerome M Hershman, Johannes Hofland, Sanjay Kalra, Gregory Kaltsas, Christian Koch, Peter Kopp, Márta Korbonits, Christopher S Kovacs, Wendy Kuohung, Blandine Laferrère, Miles Levy, Elizabeth A McGee, Robert McLachlan, John E Morley, Maria New, Jonathan Purnell, Rakesh Sahay, Frederick Singer, Mark A Sperling, Constantine A Stratakis, Dace L Tren, Don P Wilson, editors., "HPA Axis and Sleep", In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. 2020 Nov 24.. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 131. Eva Fries, Lucia Dettenborn, Clemens Kirschbaum, "The cortisol awakening response (CAR): facts and future directions", Int J Psychophysiol. 2009 Apr;72(1):67-73. doi: 10.1016/j.ijpsycho.2008.03.014. Epub 2008 Sep 30.. https://pubmed.ncbi.nlm.nih.gov/18854200/
  • 132. Nicolas C. Nicolaides, Alexandros N. Vgontzas, Ilia Kritikou, George Chrousos Kenneth R Feingold, Bradley Anawalt, Alison Boyce, George Chrousos, Wouter W de Herder, Ketan Dhatariya, Kathleen Dungan, Jerome M Hershman, Johannes Hofland, Sanjay Kalra, Gregory Kaltsas, Christian Koch, Peter Kopp, Márta Korbonits, Christopher S Kovacs, Wendy Kuohung, Blandine Laferrère, Miles Levy, Elizabeth A McGee, Robert McLachlan, John E Morley, Maria New, Jonathan Purnell, Rakesh Sahay, Frederick Singer, Mark A Sperling, Constantine A Stratakis, Dace L Tren, Don P Wilson, editors., "HPA Axis and Sleep", In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. 2020 Nov 24.. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 133. Al Sunni A, Latif R., "Effects of chocolate intake on Perceived Stress; a Controlled Clinical Study", Int J Health Sci (Qassim). 2014 Oct;8(4):393-401. PMID: 25780358; PMCID: PMC4350893.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350893/
  • 134. Steptoe A, Gibson EL, Vuononvirta R, Williams ED, Hamer M, Rycroft JA, Erusalimsky JD, Wardle J., "The effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trial", Psychopharmacology (Berl). 2007 Jan;190(1):81-9. doi: 10.1007/s00213-006-0573-2. Epub 2006 Sep 30. PMID: 17013636. https://pubmed.ncbi.nlm.nih.gov/17013636/
  • 135. "Calm Kit", https://www.gaiaherbs.com/products/calm-kit
  • 136. Hussain J, Cohen M., "Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review", Evid Based Complement Alternat Med. 2018 Apr 24;2018:1857413. doi: 10.1155/2018/1857413. PMID: 29849692; PMCID: PMC5941775.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941775/
  • 137. Statista Research Department, "Digital device addiction among users in the United States as of September 2022, by stress level", https://www.statista.com. https://www.statista.com/statistics/1343810/us-users-addiction-digital-devices-by-stress-level/
  • 138. Singh KV, Gautam R, Meena R, Nirala JP, Jha SK, Rajamani P., "Effect of mobile phone radiation on oxidative stress, inflammatory response, and contextual fear memory in Wistar rat", Environ Sci Pollut Res Int. 2020 Jun;27(16):19340-19351. doi: 10.1007/s11356-020-07916-z. Epub 2020 Mar 24. PMID: 32212071.. https://pubmed.ncbi.nlm.nih.gov/32212071/
  • 139. Eric Suni, "Technology in the Bedroom", https://www.sleepfoundation.org/bedroom-environment/technology-in-the-bedroom
  • 140. Barton J, Rogerson M, "The importance of greenspace for mental health", BJPsych Int. 2017 Nov 1;14(4):79-81. doi: 10.1192/s2056474000002051. PMID: 29093955; PMCID: PMC5663018.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663018/
  • 141. Lee MS, Lee J, Park BJ, Miyazaki Y., "Interaction with indoor plants may reduce psychological and physiological stress by suppressing autonomic nervous system activity in young adults: a randomized crossover study", J Physiol Anthropol. 2015 Apr 28;34(1):21. doi: 10.1186/s40101-015-0060-8. PMID: 25928639; PMCID: PMC4419447.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419447/
  • 142. Alexander Panossian, Georg Wikman, "Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity", Pharmaceuticals 2010, 3(1), 188-224; https://doi.org/10.3390/ph3010188. https://www.mdpi.com/1424-8247/3/1/188
  • 143. Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J., "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine.", Molecules. 2009 Jul 3;14(7):2373-93. doi: 10.3390/molecules14072373. PMID: 19633611; PMCID: PMC6255378.. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 144. Sanjaya Chauhan,Manoj K. Srivastava,Anklesh K. Pathak, "Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial", 20 July 2022 https://doi.org/10.1002/hsr2.741. https://onlinelibrary.wiley.com/doi/10.1002/hsr2.741
  • 145. UT News, "Stress Hormone Blocks Testosterone’s Effects, Study Shows", The University of Texas at Austin. https://news.utexas.edu/2010/09/27/stress-hormone-blocks-testosterones-effects-study-shows/
  • 146. Centers for Disease Control and Prevention, "Data and Statistics", cdc.gov. https://www.cdc.gov/sleep/data_statistics.html
  • 147. Krishnan V, Collop NA, "Gender differences in sleep disorders", Curr Opin Pulm Med. 2006 Nov;12(6):383-9. doi: 10.1097/01.mcp.0000245705.69440.6a. PMID: 17053485.. https://pubmed.ncbi.nlm.nih.gov/17053485/
  • 148. Office of Communications, "How does inadequate sleep affect health?", National Institutes of Health. nichd.nih.gov/health/topics/sleep/conditioninfo/inadequate-sleep#
  • 149. Gorelick J, Rosenberg R, Smotrich A, Hanuš L, Bernstein N., "Hypoglycemic activity of withanolides and elicitated Withania somnifera", Phytochemistry. 2015 Aug;116:283-289. doi: 10.1016/j.phytochem.2015.02.029. Epub 2015 Mar 18. PMID: 25796090.. https://pubmed.ncbi.nlm.nih.gov/25796090/
  • 150. Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A, "Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study.", Evid Based Complement Alternat Med. 2013;2013:571420. doi: 10.1155/2013/571420. Epub 2013 Nov 28. PMID: 24371462; PMCID: PMC3863556.. https://pubmed.ncbi.nlm.nih.gov/24371462/
  • 151. Lopresti AL, Drummond PD, Smith SJ., "A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males", American Journal of Men’s Health. 2019;13(2). doi:10.1177/1557988319835985. https://journals.sagepub.com/doi/full/10.1177/1557988319835985
  • 152. American Psychological Association, "Stress in America", APA.org. https://www.apa.org/news/press/releases/stress/2022/march-2022-survival-mode
  • 153. Aviva USA, "Aviva survey finds financial situation is top stressor for men and links stress levels to weight gain", https://www.aviva.com/newsroom/news-releases/2012/06/usa-aviva-survey-finds-financial-situation-is-top-stressor-for-men-and-links-stress-levels-to-weight-gain-16940/
  • 154. Maes MF, van Baar HM, van Ginkel CJ., "Occupational allergic contact dermatitis from the mushroom White Pom Pom (Hericium erinaceum)", Contact Dermatitis. 1999 May;40(5):289-90. doi: 10.1111/j.1600-0536.1999.tb06073.x. PMID: 10344494.. https://pubmed.ncbi.nlm.nih.gov/10344494/
  • 155. Nakatsugawa M, Takahashi H, Takezawa C, Nakajima K, Harada K, Sugawara Y, Kobayashi S, Kondo T, Abe S, "Hericium erinaceum (yamabushitake) extract-induced acute respiratory distress syndrome monitored by serum surfactant proteins", Intern Med. 2003 Dec;42(12):1219-22. doi: 10.2169/internalmedicine.42.1219. PMID: 14714963.. https://pubmed.ncbi.nlm.nih.gov/14714963/
  • 156. Lo HC, Hsu TH, Lee CH., "Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus", Int J Med Mushrooms. 2020;22(5):417-429. doi: 10.1615/IntJMedMushrooms.2020034560. PMID: 32749097. https://pubmed.ncbi.nlm.nih.gov/32749097/
  • 157. Kathy Abascal, B.S., J.D., RH. And Eric Yarnell, N.D. R.H, "A Turkey Tails Polysaccharide as an Immunochemotherapy Agent in Cancer", August 2007. https://www.researchgate.net/publication/244889954_A_Turkey_Tails_Polysaccharide_as_an_Immunochemotherapy_Agent_in_Cancer
  • 158. Dickson, J.M.; Moberly, N.J.; Preece, D.; Dodd, A.; Huntley, C.D, "Self-Regulatory Goal Motivational Processes in Sustained New Year Resolution Pursuit and Mental Wellbeing", Int. J. Environ. Res. Public Health 2021, 18, 3084. https://www.mdpi.com/1660-4601/18/6/3084
  • 159. Aguiar S, Borowski T, "Neuropharmacological review of the nootropic herb Bacopa monnieri", Rejuvenation Res. 2013 Aug;16(4):313-26. doi: 10.1089/rej.2013.1431. PMID: 23772955; PMCID: PMC3746283.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746283/
  • 160. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G., "Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders", Neurotherapeutics. 2019 Jul;16(3):666-674. doi: 10.1007/s13311-019-00767-8. PMID: 31376068; PMCID: PMC6694352. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694352/
  • 161. Avgerinos KI, Vrysis C, Chaitidis N, Kolotsiou K, Myserlis PG, Kapogiannis D, "Effects of saffron (Crocus sativus L.) on cognitive function. A systematic review of RCTs", Neurol Sci. 2020 Oct;41(10):2747-2754. doi: 10.1007/s10072-020-04427-0. Epub 2020 May 23. PMID: 32445136; PMCID: PMC7484083.. https://pubmed.ncbi.nlm.nih.gov/32445136/
  • 162. Scholey A, Gibbs A, Neale C, Perry N, Ossoukhova A, Bilog V, Kras M, Scholz C, Sass M, Buchwald-Werner S, "Anti-stress effects of lemon balm-containing foods", Nutrients. 2014 Oct 30;6(11):4805-21. doi: 10.3390/nu6114805. PMID: 25360512; PMCID: PMC4245564.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245564/
  • 163. Tiralongo E, Wee SS, Lea RA, "Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial", Nutrients. 2016 Mar 24;8(4):182. doi: 10.3390/nu8040182. PMID: 27023596; PMCID: PMC4848651.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848651/
  • 164. Zakay-Rones Z, Thom E, Wollan T, Wadstein J, "Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections", J Int Med Res. 2004 Mar-Apr;32(2):132-40. doi: 10.1177/147323000403200205. PMID: 15080016.. https://pubmed.ncbi.nlm.nih.gov/15080016/
  • 165. Kennedy DO, Little W, Scholey AB, "Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)", Psychosom Med. 2004 Jul-Aug;66(4):607-13. doi: 10.1097/01.psy.0000132877.72833.71. PMID: 15272110.. https://pubmed.ncbi.nlm.nih.gov/15272110/
  • 166. Islam MA, Haque MA, Rahman MA, Hossen F, Reza M, Barua A, Marzan AA, Das T, Kumar Baral S, He C, Ahmed F, Bhattacharya P, Jakariya M, "A Review on Measures to Rejuvenate Immune System: Natural Mode of Protection Against Coronavirus Infection", Front Immunol. 2022 Mar 15;13:837290. doi: 10.3389/fimmu.2022.837290. PMID: 35371007; PMCID: PMC8965011. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965011/
  • 167. Aubert P, Guinobert I, Blondeau C, Bardot V, Ripoche I, Chalard P, Neunlist M, "Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract of Melissa officinalis L. on Intestinal Motility: An Ex Vivo Study", J Med Food. 2019 Jul;22(7):653-662. doi: 10.1089/jmf.2018.0154. Epub 2019 Apr 16. PMID: 30990736; PMCID: PMC6653806. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653806/
  • 168. Soomi Lee, Ph.D, "Naturally Occurring Consecutive Sleep Loss and Day-to-Day Trajectories of Affective and Physical Well-Being", Annals of Behavioral Medicine, Volume 56, Issue 4, April 2022, Pages 393–404. https://academic.oup.com/abm/advance-article-abstract/doi/10.1093/abm/kaab055/6314765?redirectedFrom=fulltext&login=false
  • 169. Centers for Disease Control and Prevention, "10 Surprising Things That Can Spike Your Blood Sugar", July 28, 2022. https://www.cdc.gov/diabetes/library/spotlights/blood-sugar.html
  • 170. Toda K, Hitoe S, Takeda S, Shimizu N, Shimoda H, "Passionflower Extract Induces High-amplitude Rhythms without Phase Shifts in the Expression of Several Circadian Clock Genes in Vitro and in Vivo", Int J Biomed Sci. 2017 Jun;13(2):84-92. PMID: 28824345; PMCID: PMC5542920. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542920/
  • 171. Hamidpour R, Hamidpour M, Hamidpour S, Shahlari M, "Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities", J Tradit Complement Med. 2015 Jan 16;5(2):66-70. doi: 10.1016/j.jtcme.2014.11.008. PMID: 26151013; PMCID: PMC4488098. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488098/
  • 172. Kirkham S, Akilen R, Sharma S, Tsiami A, "The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance", Diabetes Obes Metab. 2009 Dec;11(12):1100-13. doi: 10.1111/j.1463-1326.2009.01094.x. PMID: 19930003. https://pubmed.ncbi.nlm.nih.gov/19930003/
  • 173. Warnke PH, Becker ST, Podschun R, Sivananthan S, Springer IN, Russo PA, Wiltfang J, Fickenscher H, Sherry E, "The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections", J Craniomaxillofac Surg. 2009 Oct;37(7):392-7. doi: 10.1016/j.jcms.2009.03.017. Epub 2009 May 26. PMID: 19473851. https://pubmed.ncbi.nlm.nih.gov/19473851/
  • 174. Whiskey E, Werneke U, Taylor D, "A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review", Int Clin Psychopharmacol. 2001 Sep;16(5):239-52. doi: 10.1097/00004850-200109000-00001. PMID: 11552767. https://pubmed.ncbi.nlm.nih.gov/11552767/
  • 175. Ng QX, Venkatanarayanan N, Ho CY, "Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis", J Affect Disord. 2017 Mar 1;210:211-221. doi: 10.1016/j.jad.2016.12.048. Epub 2017 Jan 3. PMID: 28064110. https://pubmed.ncbi.nlm.nih.gov/28064110/
  • 176. Boersma P, Black LI, Ward BW, "Prevalence of Multiple Chronic Conditions Among US Adults, 2018", Prev Chronic Dis 2020;17:200130. https://www.cdc.gov/pcd/issues/2020/20_0130.htm
  • 177. Uchiyama F, Jikyo T, Takeda R, Ogata M, "Lepidium meyenii (Maca) enhances the serum levels of luteinising hormone in female rats", J Ethnopharmacol. 2014 Feb 3;151(2):897-902. doi: 10.1016/j.jep.2013.11.058. Epub 2013 Dec 11. PMID: 24333960.. https://pubmed.ncbi.nlm.nih.gov/24333960/
  • 178. Louis GM, Lum KJ, Sundaram R, Chen Z, Kim S, Lynch CD, Schisterman EF, Pyper C., "Stress reduces conception probabilities across the fertile window: evidence in support of relaxation", Fertil Steril. 2011 Jun;95(7):2184-9. doi: 10.1016/j.fertnstert.2010.06.078. Epub 2010 Aug 5. PMID: 20688324; PMCID: PMC2975045.. https://pubmed.ncbi.nlm.nih.gov/20688324/
  • 179. Rosales-Hartshorn M, "Maca: Botanical medicine from the andes", Adv Food Technol Nutr Sci Open J. 2015; 1(2): e1-e6. doi: 10.17140/AFTNSOJ-1-e001. https://www.openventio.org/Volume1-Issue2/Maca-Botanical-Medicine-from-the-Andes-AFTNSOJ-1-e001.pdf
  • 180. Cleveland Clinic medical professional, "Thyroid Hormone", 02/15/2022.. https://my.clevelandclinic.org/health/articles/22391-thyroid-hormone
  • 181. Laumann EO, Paik A, Rosen RC., "Sexual dysfunction in the United States: prevalence and predictors", JAMA. 1999 Feb 10;281(6):537-44. doi: 10.1001/jama.281.6.537. Erratum in: JAMA 1999 Apr 7;281(13):1174. PMID: 10022110.. https://pubmed.ncbi.nlm.nih.gov/10022110/
  • 182. Centers for Disease Control and Prevention, "QuickStats: Percentage of Adults Who Often Felt Very Tired or Exhausted in the Past 3 Months,* by Sex and Age Group - National Health Interview Survey, United States, 2010-2011", https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6214a5.htm?s_cid=mm6214a5_w
  • 183. Fernandez-Jimenez MC, Moreno G, Wright I, Shih PC, Vaquero MP, Remacha AF, "Iron Deficiency in Menstruating Adult Women: Much More than Anemia", Womens Health Rep (New Rochelle). 2020 Jan 29;1(1):26-35. doi: 10.1089/whr.2019.0011. PMID: 33786470; PMCID: PMC7784796.. https://pubmed.ncbi.nlm.nih.gov/33786470/
  • 184. Zhong Ai, Ai-Fang Cheng, Yuan-Tao Yu, Long-Jiang Yu, and Wenwen Jin., "Antidepressant-Like Behavioral, Anatomical, and Biochemical Effects of Petroleum Ether Extract from Maca (Lepidium meyenii) in Mice Exposed to Chronic Unpredictable Mild Stress", Journal of Medicinal Food.May 2014.535-542.. https://www.liebertpub.com/doi/10.1089/jmf.2013.2950
  • 185. Office on Women’s Health, "Stress and your health", February 17, 2021. https://www.womenshealth.gov/mental-health/good-mental-health/stress-and-your-health
  • 186. Facchinetti F, Borella P, Sances G, Fioroni L, Nappi RE, Genazzani AR., "Oral magnesium successfully relieves premenstrual mood changes", Obstet Gynecol. 1991 Aug;78(2):177-81. PMID: 2067759.. https://pubmed.ncbi.nlm.nih.gov/2067759/
  • 187. Rocha Filho EA, Lima JC, Pinho Neto JS, Montarroyos U, "Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double blind, placebo-controlled study", Reprod Health. 2011 Jan 17;8:2. doi: 10.1186/1742-4755-8-2. PMID: 21241460; PMCID: PMC3033240.. https://pubmed.ncbi.nlm.nih.gov/21241460/
  • 188. Lee MS, Shin BC, Yang EJ, Lim HJ, Ernst E, "Maca (Lepidium meyenii) for treatment of menopausal symptoms: A systematic review", Maturitas. 2011 Nov;70(3):227-33. doi: 10.1016/j.maturitas.2011.07.017. Epub 2011 Aug 15. PMID: 21840656. https://pubmed.ncbi.nlm.nih.gov/21840656/
  • 189. Ross K., "Nutritional management of surgically induced menopause: A case report", Womens Health (Lond). 2021 Jan-Dec;17:17455065211031492. doi: 10.1177/17455065211031492. PMID: 34253105; PMCID: PMC8280844.. https://pubmed.ncbi.nlm.nih.gov/34253105/
  • 190. Stojanovska L, Law C, Lai B, Chung T, Nelson K, Day S, Apostolopoulos V, Haines C, "Maca reduces blood pressure and depression, in a pilot study in postmenopausal women", Climacteric. 2015 Feb;18(1):69-78. doi: 10.3109/13697137.2014.929649. Epub 2014 Aug 7. PMID: 24931003.. https://pubmed.ncbi.nlm.nih.gov/24931003/
  • 191. Endocrine Society, "Menopause and Bone Loss", January 24, 2022. https://www.endocrine.org/patient-engagement/endocrine-library/menopause-and-bone-loss
  • 192. Zhang Y, Yu L, Ao M, Jin W, "Effect of ethanol extract of Lepidium meyenii Walp. on osteoporosis in ovariectomized rat.", J Ethnopharmacol. 2006 Apr 21;105(1-2):274-9. doi: 10.1016/j.jep.2005.12.013. Epub 2006 Feb 8. PMID: 16466876.. https://pubmed.ncbi.nlm.nih.gov/16466876/
  • 193. JOUR, Gonzales, C., Cárdenas-Valencia, I.,Leiva-Revilla, J.,Anza-Ramirez, C., Rubio, J.,Gonzales, G.,, "Effects of Different Varieties of Maca (Lepidium meyenii) on Bone Structure in Ovariectomized Rats", VL;17, DO;10.1159/000315214, Forschende Komplementärmedizin (2006). https://www.researchgate.net/publication/45114055_Effects_of_Different_Varieties_of_Maca_Lepidium_meyenii_on_Bone_Structure_in_Ovariectomized_Rats
  • 194. Parker G, Gibson NA, Brotchie H, Heruc G, Rees AM, Hadzi-Pavlovic D, "Omega-3 fatty acids and mood disorders", Am J Psychiatry. 2006 Jun;163(6):969-78. doi: 10.1176/ajp.2006.163.6.969. Erratum in: Am J Psychiatry. 2006 Oct;163(10):1842. PMID: 16741195.. https://pubmed.ncbi.nlm.nih.gov/16741195/
  • 195. Perera G, Hay R., "A guide to antibiotic resistance in bacterial skin infections.", J Eur Acad Dermatol Venereol. 2005 Sep;19(5):531-45. doi: 10.1111/j.1468-3083.2005.01296.x. PMID: 16164705.. https://pubmed.ncbi.nlm.nih.gov/16164705/
  • 196. Lombrea A, Antal D, Ardelean F, Avram S, Pavel IZ, Vlaia L, Mut AM, Diaconeasa Z, Dehelean CA, Soica C, Danciu C, "A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil.", Int J Mol Sci. 2020 Dec 17;21(24):9653. doi: 10.3390/ijms21249653. PMID: 33348921; PMCID: PMC7765853.. https://pubmed.ncbi.nlm.nih.gov/33348921/
  • 197. Ragi J, Pappert A, Rao B, Havkin-Frenkel D, Milgraum S, "Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy", J Drugs Dermatol. 2011 Oct;10(10):1168-72. PMID: 21968667.. https://pubmed.ncbi.nlm.nih.gov/21968667/
  • 198. Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, Ramadan MA, "Origanum vulgare L. Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study", Molecules. 2018 Aug 28;23(9):2164. doi: 10.3390/molecules23092164. PMID: 30154336; PMCID: PMC6225355. https://pubmed.ncbi.nlm.nih.gov/30154336/
  • 199. Shinjyo N, Waddell G, Green J., "Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis", J Evid Based Integr Med. 2020 Jan-Dec;25:2515690X20967323. doi: 10.1177/2515690X20967323. PMID: 33086877; PMCID: PMC7585905.. https://pubmed.ncbi.nlm.nih.gov/33086877/
  • 200. National Institute of Mental Health, "Anxiety Disorders", April 2022. https://www.nimh.nih.gov/health/topics/anxiety-disorders
  • 201. Joseph DN, Whirledge S, "Stress and the HPA Axis: Balancing Homeostasis and Fertility", Int J Mol Sci. 2017 Oct 24;18(10):2224. doi: 10.3390/ijms18102224. PMID: 29064426; PMCID: PMC5666903. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666903/
  • 202. Bhatnagar M, Sharma D, Salvi M, "Neuroprotective effects of Withania somnifera dunal.: A possible mechanism", Neurochem Res. 2009 Nov;34(11):1975-83. doi: 10.1007/s11064-009-9987-7. Epub 2009 May 15. PMID: 19444606. https://pubmed.ncbi.nlm.nih.gov/19444606/
  • 203. Ittermann T, Völzke H, Baumeister SE, Appel K, Grabe HJ, "Diagnosed thyroid disorders are associated with depression and anxiety", Soc Psychiatry Psychiatr Epidemiol. 2015 Sep;50(9):1417-25. doi: 10.1007/s00127-015-1043-0. Epub 2015 Mar 17. PMID: 25777685. https://pubmed.ncbi.nlm.nih.gov/25777685/
  • 204. Sait Gönen M, Kisakol G, Savas Cilli A, Dikbas O, Gungor K, Inal A, Kaya A, "Assessment of anxiety in subclinical thyroid disorders", Endocr J. 2004 Jun;51(3):311-5. doi: 10.1507/endocrj.51.311. PMID: 15256776.. Endocr J. 2004 Jun;51(3):311-5. doi: 10.1507/endocrj.51.311. PMID: 15256776.
  • 205. Rashad, N.M., Samir, G.M., "Prevalence, risks, and comorbidity of thyroid dysfunction: a cross-sectional epidemiological study.", Egypt J Intern Med 31, 635–641 (2019). https://ejim.springeropen.com/articles/10.4103/ejim.ejim_22_19
  • 206. Hanson JA, Huecker MR., "Sleep Deprivation", [Updated 2022 Sep 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from:. https://www.ncbi.nlm.nih.gov/books/NBK547676/
  • 207. Cohen PA, Benner C, McCormick D, "Use of a pharmaceutically adulterated dietary supplement, Pai You Guo, among Brazilian-born women in the United States", J Gen Intern Med. 2012 Jan;27(1):51-6. doi: 10.1007/s11606-011-1828-0. Epub 2011 Aug 16. PMID: 21845487; PMCID: PMC3250540. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250540/
  • 208. Jesse Hirsch, "Arsenic, Lead Found in Popular Protein Supplements", March 12, 2018. https://www.consumerreports.org/dietary-supplements/heavy-metals-in-protein-supplements/
  • 209. Gérard P, "Gut microbiota and obesity", Cell Mol Life Sci. 2016 Jan;73(1):147-62. doi: 10.1007/s00018-015-2061-5. Epub 2015 Oct 12. PMID: 26459447.. https://pubmed.ncbi.nlm.nih.gov/26459447/
  • 210. Kalra A, Yetiskul E, Wehrle CJ, Tuma F, "Physiology, Liver", 2022 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 30571059. https://pubmed.ncbi.nlm.nih.gov/30571059/
  • 211. National Library of Medicine, "How does the liver work?", August 22, 2016, Bookshelf ID: NBK279393. https://www.ncbi.nlm.nih.gov/books/NBK279393/
  • 212. Cleveland Clinic, "Metabolism", 800.223.2273, 08/30/2021. https://my.clevelandclinic.org/health/body/21893-metabolism
  • 213. David O. Norris, "Endocrine system", Health & Medicine, Anatomy & Physiology, Nov 16, 202. https://www.britannica.com/science/endocrine-system/Other-vertebrate-endocrine-glands
  • 214. Tomiyama AJ, "Stress and Obesity", Annu Rev Psychol. 2019 Jan 4;70:703-718. doi: 10.1146/annurev-psych-010418-102936. Epub 2018 Jun 21. PMID: 29927688.. https://pubmed.ncbi.nlm.nih.gov/29927688/
  • 215. Joseph DN, Whirledge S., "Stress and the HPA Axis: Balancing Homeostasis and Fertility", Int J Mol Sci. 2017 Oct 24;18(10):2224. doi: 10.3390/ijms18102224. PMID: 29064426; PMCID: PMC5666903.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666903/
  • 216. Zhu, H.,Xu, W.,Wang, N.,Jiang, W.,Cheng, Y.,Guo, Y.,Yao, W.,Hu, B.,Du, P.,Qian, H, "Anti-fatigue effect of Lepidium meyenii Walp. (Maca) on preventing mitochondria-mediated muscle damage and oxidative stress in vivo and vitro", Food Funct., 2021,12, 3132-3141. https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo00383f/unauth
  • 217. Lee MS, Shin BC, Yang EJ, Lim HJ, Ernst E., "Maca (Lepidium meyenii) for treatment of menopausal symptoms: A systematic review", Maturitas. 2011 Nov;70(3):227-33. doi: 10.1016/j.maturitas.2011.07.017. Epub 2011 Aug 15. PMID: 21840656.. https://pubmed.ncbi.nlm.nih.gov/21840656/
  • 218. Stojanovska L, Law C, Lai B, Chung T, Nelson K, Day S, Apostolopoulos V, Haines C, "Maca reduces blood pressure and depression, in a pilot study in postmenopausal women", Climacteric. 2015 Feb;18(1):69-78. doi: 10.3109/13697137.2014.929649. Epub 2014 Aug 7. PMID: 24931003. https://pubmed.ncbi.nlm.nih.gov/24931003/
  • 219. Brooks NA, Wilcox G, Walker KZ, Ashton JF, Cox MB, Stojanovska L., "Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content", Menopause. 2008 Nov-Dec;15(6):1157-62. doi: 10.1097/gme.0b013e3181732953. PMID: 18784609.. https://pubmed.ncbi.nlm.nih.gov/18784609/
  • 220. Canbay A, Bechmann L, Gerken G, "Lipid metabolism in the liver", Z Gastroenterol. 2007 Jan;45(1):35-41. doi: 10.1055/s-2006-927368. PMID: 17236119.. https://pubmed.ncbi.nlm.nih.gov/17236119/
  • 221. "Metabolic Functions of the Liver", http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/metabolic.html
  • 222. Monteiro MP, Batterham RL, "The Importance of the Gastrointestinal Tract in Controlling Food Intake and Regulating Energy Balance", Gastroenterology. 2017 May;152(7):1707-1717.e2. doi: 10.1053/j.gastro.2017.01.053. Epub 2017 Feb 11. PMID: 28193513. https://pubmed.ncbi.nlm.nih.gov/28193513/
  • 223. Gérard P, "Gut microbiota and obesity", Cell Mol Life Sci. 2016 Jan;73(1):147-62. doi: 10.1007/s00018-015-2061-5. Epub 2015 Oct 12. PMID: 26459447.. https://pubmed.ncbi.nlm.nih.gov/26459447/
  • 224. John GK, Mullin GE, "The Gut Microbiome and Obesity", Curr Oncol Rep. 2016 Jul;18(7):45. doi: 10.1007/s11912-016-0528-7. PMID: 27255389. https://pubmed.ncbi.nlm.nih.gov/27255389/
  • 225. FoodSafety, "The Threat of Dietary Supplements Containing Dangerously High Levels of Extremely Concentrated or Pure Caffeine", https://www.foodsafety.gov/blog/threat-dietary-supplements-containing-dangerously-high-levels-extremely-concentrated-or-pure
  • 226. Leigh Ann Anderson, PharmD, "Side Effects of Weight Loss Drugs (Diet Pills)", Articles, Weight Loss, June 22, 2021. https://www.drugs.com/article/side-effects-weight-loss-drugs.html
  • 227. Krenn L., "Die Passionsblume (Passiflora incarnata L.)--ein bewährtes pflanzliches Sedativum [Passion Flower (Passiflora incarnata L.)--a reliable herbal sedative]", Wien Med Wochenschr. 2002;152(15-16):404-6. German. doi: 10.1046/j.1563-258x.2002.02062.x. PMID: 12244887.. https://pubmed.ncbi.nlm.nih.gov/12244887/
  • 228. Ngan A, Conduit R., "A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality", Phytother Res. 2011 Aug;25(8):1153-9. doi: 10.1002/ptr.3400. Epub 2011 Feb 3. PMID: 21294203.. https://pubmed.ncbi.nlm.nih.gov/21294203/
  • 229. Appel K, Rose T, Fiebich B, Kammler T, Hoffmann C, Weiss G, "Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L", Phytother Res. 2011 Jun;25(6):838-43. doi: 10.1002/ptr.3352. Epub 2010 Nov 19. PMID: 21089181. https://pubmed.ncbi.nlm.nih.gov/21089181/
  • 230. Toda K, Hitoe S, Takeda S, Shimizu N, Shimoda H., "Passionflower Extract Induces High-amplitude Rhythms without Phase Shifts in the Expression of Several Circadian Clock Genes in Vitro and in Vivo", Int J Biomed Sci. 2017 Jun;13(2):84-92. PMID: 28824345; PMCID: PMC5542920.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542920/
  • 231. Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M, "Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam", J Clin Pharm Ther. 2001 Oct;26(5):363-7. doi: 10.1046/j.1365-2710.2001.00367.x. PMID: 11679026.. https://pubmed.ncbi.nlm.nih.gov/11679026/
  • 232. Fahami F, Asali Z, Aslani A, Fathizadeh N., "A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers", Iran J Nurs Midwifery Res. 2010 Fall;15(4):202-7. PMID: 22049281; PMCID: PMC3203277. https://pubmed.ncbi.nlm.nih.gov/22049281/
  • 233. U.S. DEPARTMENT OF AGRICULTURE, "Food Data Central Search Results", STEEL CUT OATS, BRANDED, FDC ID: 1544557; FDC Published:3/19/2021. https://fdc.nal.usda.gov/fdc-app.html#/food-details/1544557/nutrients
  • 234. U.S. DEPARTMENT OF AGRICULTURE, "Food Data Central Search Results", ROLLED OATS, BRANDED, FDC ID: 1136417; FDC Published:11/13/2020. https://fdc.nal.usda.gov/fdc-app.html#/food-details/1136417/nutrients
  • 235. Tosh SM, Chu Y, "Systematic review of the effect of processing of whole-grain oat cereals on glycaemic response", Br J Nutr. 2015 Oct 28;114(8):1256-62. doi: 10.1017/S0007114515002895. Epub 2015 Sep 2. PMID: 26330200.. https://pubmed.ncbi.nlm.nih.gov/26330200/
  • 236. Paudel D, Dhungana B, Caffe M, Krishnan P., "A Review of Health-Beneficial Properties of Oats", Foods. 2021 Oct 26;10(11):2591. doi: 10.3390/foods10112591. PMID: 34828872; PMCID: PMC8625765. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625765/
  • 237. Valeur J, Puaschitz NG, Midtvedt T, Berstad A, "Oatmeal porridge: impact on microflora-associated characteristics in healthy subjects", Br J Nutr. 2016 Jan 14;115(1):62-7. doi: 10.1017/S0007114515004213. Epub 2015 Oct 29. PMID: 26511097.. https://pubmed.ncbi.nlm.nih.gov/26511097/
  • 238. Centers for Disease Control and Prevention, "The Facts, Stats, and Impacts of Diabetes", cdc.gov. https://www.cdc.gov/diabetes/library/spotlights/diabetes-facts-stats.html
  • 239. Uusitupa M, Khan TA, Viguiliouk E, Kahleova H, Rivellese AA, Hermansen K, Pfeiffer A, Thanopoulou A, Salas-Salvadó J, Schwab U, Sievenpiper JL, "Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis", Nutrients. 2019 Nov 1;11(11):2611. doi: 10.3390/nu11112611. PMID: 31683759; PMCID: PMC6893436. https://pubmed.ncbi.nlm.nih.gov/31683759/
  • 240. Centers for Disease Control and Prevention, "Prediabetes – Your Chance to Prevent Type 2 Diabetes", cdc.gov. https://www.cdc.gov/diabetes/basics/prediabetes.html
  • 241. Tappy L., Gugolz E., Wursch P., "Effects of Breakfast Cereals Containing Various Amounts of -Glucan Fibers on Plasma Glucose and Insulin Responses in NIDDM Subjects", Diabetes Care. 1996;19:831–834. doi: 10.2337/diacare.19.8.831. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625765/#B39-foods-10-02591
  • 242. Battilana P., Ornstein K., Minehira K., Schwarz J.M., Acheson K., Schneiter P., Burri J., Jéquier E., Tappy L., "Mechanisms of action of β-glucan in postprandial glucose metabolism in healthy men", Eur. J. Clin. Nutr. 2001;55:327–333. doi: 10.1038/sj.ejcn.1601160. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625765/#B129-foods-10-02591
  • 243. Li X, Cai X, Ma X, Jing L, Gu J, Bao L, Li J, Xu M, Zhang Z, Li Y, "Short- and Long-Term Effects of Wholegrain Oat Intake on Weight Management and Glucolipid Metabolism in Overweight Type-2 Diabetics: A Randomized Control Trial", Nutrients. 2016 Sep 7;8(9):549. doi: 10.3390/nu8090549. PMID: 27618090; PMCID: PMC5037534.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037534/
  • 244. Sur R, Nigam A, Grote D, Liebel F, Southall MD, "Avenanthramides, polyphenols from oats, exhibit anti-inflammatory and anti-itch activity", Arch Dermatol Res. 2008 Nov;300(10):569-74. doi: 10.1007/s00403-008-0858-x. Epub 2008 May 7. PMID: 18461339.. https://pubmed.ncbi.nlm.nih.gov/18461339/
  • 245. Ciecierska A, Drywień ME, Hamulka J, Sadkowski T, "Nutraceutical functions of beta-glucans in human nutrition", Rocz Panstw Zakl Hig. 2019;70(4):315-324. doi: 10.32394/rpzh.2019.0082. PMID: 31960663. https://pubmed.ncbi.nlm.nih.gov/31960663/
  • 246. Monique Tello, MD, MPH, "Fiber-full eating for better health and lower cholesterol", HARVARD HEALTH BLOG, June 24, 2019. https://www.health.harvard.edu/blog/fiber-full-eating-for-better-health-and-lower-cholesterol-2019062416819
  • 247. Bhargava K, Conti DS, da Rocha SR, et al., "Application of an oregano oil nanoemulsion to the control of foodborne bacteria on fresh lettuce", Food Microbiol. 2015;47:69–73. http://dx.doi.org/10.1016/j.fm.2014.11.007
  • 248. Sienkiewicz M, Wasiela M, Głowacka A., "[The antibacterial activity of oregano essential oil (Origanum heracleoticum L.) against clinical strains of Escherichia coli and Pseudomonas aeruginosa", Med Dosw Mikrobiol. 2012;64(4):297-307. Polish. PMID: 23484421.. https://pubmed.ncbi.nlm.nih.gov/23484421/
  • 249. Krenn L., "[Passion Flower (Passiflora incarnata L.)--a reliable herbal sedative]", Wien Med Wochenschr. 2002;152(15-16):404-6. German. doi: 10.1046/j.1563-258x.2002.02062.x. PMID: 12244887.. https://pubmed.ncbi.nlm.nih.gov/12244887/
  • 250. Ngan A, Conduit R., "A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality.", Phytother Res. 2011 Aug;25(8):1153-9. doi: 10.1002/ptr.3400. Epub 2011 Feb 3. PMID: 21294203.. https://pubmed.ncbi.nlm.nih.gov/21294203/
  • 251. Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M, "Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam", J Clin Pharm Ther. 2001 Oct;26(5):363-7. doi: 10.1046/j.1365-2710.2001.00367.x. PMID: 11679026.. https://pubmed.ncbi.nlm.nih.gov/11679026/
  • 252. Appel K, Rose T, Fiebich B, Kammler T, Hoffmann C, Weiss G, "Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L", Phytother Res. 2011 Jun;25(6):838-43. doi: 10.1002/ptr.3352. Epub 2010 Nov 19. PMID: 21089181.. https://pubmed.ncbi.nlm.nih.gov/21089181/
  • 253. Movafegh, Ali MD*; Alizadeh, Reza MD†; Hajimohamadi, Fatimah MD‡; Esfehani, Fatimah MD†; Nejatfar, Mohmad MD†., "Preoperative Oral Passiflora Incarnata Reduces Anxiety in Ambulatory Surgery Patients: A Double-Blind, Placebo-Controlled Study", Anesthesia & Analgesia 106(6):p 1728-1732, June 2008. | DOI: 10.1213/ane.0b013e318172c3f9. https://journals.lww.com/anesthesia-analgesia/Fulltext/2008/06000/Preoperative_Oral_Passiflora_Incarnata_Reduces.19.aspx
  • 254. Dantas LP, de Oliveira-Ribeiro A, de Almeida-Souza LM, Groppo FC, "Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction", Med Oral Patol Oral Cir Bucal. 2017 Jan 1;22(1):e95-e101. doi: 10.4317/medoral.21140. PMID: 27918731; PMCID: PMC5217504.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217504/
  • 255. Fuller-Thomson E, Carrique L, MacNeil A., "Generalized anxiety disorder among adults with attention deficit hyperactivity disorder", J Affect Disord. 2022 Feb 15;299:707-714. doi: 10.1016/j.jad.2021.10.020. Epub 2021 Nov 16. PMID: 34799150.. https://pubmed.ncbi.nlm.nih.gov/34799150/
  • 256. Trompetter I, Krick B, Weiss G, "Herbal triplet in treatment of nervous agitation in children", Wien Med Wochenschr. 2013 Feb;163(3-4):52-7. doi: 10.1007/s10354-012-0165-1. Epub 2012 Nov 22. PMID: 23179673; PMCID: PMC3580146.. https://pubmed.ncbi.nlm.nih.gov/23179673/
  • 257. National, Center for Complimentary and Integrative Health, "Passionflower", https://www.nccih.nih.gov/health/passionflower
  • 258. Mishra LC, Singh BB, Dagenais S., "Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review", Altern Med Rev. 2000 Aug;5(4):334-46. PMID: 10956379.. https://pubmed.ncbi.nlm.nih.gov/10956379/
  • 259. Patel SB, Rao NJ, Hingorani LL, "Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study", J Ayurveda Integr Med. 2016 Mar;7(1):30-7. doi: 10.1016/j.jaim.2015.08.001. Epub 2016 May 24. PMID: 27297507; PMCID: PMC4910650.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910650/
  • 260. Tandon N, Yadav SS., "Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments", J Ethnopharmacol. 2020 Jun 12;255:112768. doi: 10.1016/j.jep.2020.112768. Epub 2020 Mar 19. PMID: 32201301.. https://pubmed.ncbi.nlm.nih.gov/32201301/
  • 261. Singh N, Bhalla M, de Jager P, Gilca M, "An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda", Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):208-13. doi: 10.4314/ajtcam.v8i5S.9. Epub 2011 Jul 3. PMID: 22754076; PMCID: PMC3252722. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/
  • 262. Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J, "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine", Molecules. 2009 Jul 3;14(7):2373-93. doi: 10.3390/molecules14072373. PMID: 19633611; PMCID: PMC6255378. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 263. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, "LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]", 2012-. Ashwagandha. [Updated 2019 May 2]. https://www.ncbi.nlm.nih.gov/books/NBK548536/
  • 264. Afroz M, Akter S, Ahmed A, Rouf R, Shilpi JA, Tiralongo E, Sarker SD, Göransson U, Uddin SJ, "Ethnobotany and Antimicrobial Peptides From Plants of the Solanaceae Family: An Update and Future Prospects", Front Pharmacol. 2020 May 7;11:565. doi: 10.3389/fphar.2020.00565. PMID: 32477108; PMCID: PMC7232569.. https://pubmed.ncbi.nlm.nih.gov/32477108/
  • 265. Sharma AK, Basu I, Singh S., "Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial", J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. PMID: 28829155.. https://pubmed.ncbi.nlm.nih.gov/28829155/
  • 267. Chengappa KNR, Brar JS, Gannon JM, Schlicht PJ, "Adjunctive Use of a Standardized Extract of Withania somnifera (Ashwagandha) to Treat Symptom Exacerbation in Schizophrenia: A Randomized, Double-Blind, Placebo-Controlled Study", J Clin Psychiatry. 2018 Jul 10;79(5):17m11826. doi: 10.4088/JCP.17m11826. PMID: 29995356.. https://pubmed.ncbi.nlm.nih.gov/29995356/
  • 268. John P. Cunha, DO, FACOEP, "ASHWAGANDHA", RxList. https://www.rxlist.com/consumer_ashwagandha/drugs-condition.htm
  • 269. Drugs.com, "Ashwagandha", https://www.drugs.com/npp/ashwagandha.html
  • 270. Deshpande A, Irani N, Balkrishnan R, Benny IR, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Med. 2020 Aug;72:28-36. doi: 10.1016/j.sleep.2020.03.012. Epub 2020 Mar 21. PMID: 32540634.. https://pubmed.ncbi.nlm.nih.gov/32540634/
  • 271. Auddy B, Hazra J, Mitra A, et al., "A standardized Withania Somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study", J Am Neutraceut Assoc 2008;11:50–6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 272. Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S, "Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants.", J Clin Med. 2021 Aug 18;10(16):3644. doi: 10.3390/jcm10163644. PMID: 34441940; PMCID: PMC8397213.. https://pubmed.ncbi.nlm.nih.gov/34441940/
  • 273. Chauhan S, Srivastava MK, Pathak AK., "Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial", Health Sci Rep. 2022 Jul 20;5(4):e741. doi: 10.1002/hsr2.741. PMID: 35873404; PMCID: PMC9297375.. https://pubmed.ncbi.nlm.nih.gov/35873404/
  • 274. Muhammad Hanif Mughal, "Turmeric polyphenols: A comprehensive review", Integrative Food, Nutrition and Metabolism. https://pdfs.semanticscholar.org/497b/30547906fe211facca4c7d01e3f95457f12a.pdf
  • 275. ScienceDirect Topics, "Curcuminoid", Obesity, 2018. https://www.sciencedirect.com/topics/medicine-and-dentistry/curcuminoid
  • 276. NCCIH, "Turmeric", https://www.nccih.nih.gov/health/turmeric
  • 277. Bahramsoltani R, Rahimi R, Farzaei MH, "Pharmacokinetic interactions of curcuminoids with conventional drugs: A review", J Ethnopharmacol. 2017 Sep 14;209:1-12. doi: 10.1016/j.jep.2017.07.022. Epub 2017 Jul 19. PMID: 28734960.. https://pubmed.ncbi.nlm.nih.gov/28734960/
  • 278. Kim DC, Ku SK, Bae JS, "Anticoagulant activities of curcumin and its derivative", BMB Rep. 2012 Apr;45(4):221-6. doi: 10.5483/bmbrep.2012.45.4.221. PMID: 22531131.. https://pubmed.ncbi.nlm.nih.gov/22531131/
  • 279. Tuntipopipat S, Zeder C, Siriprapa P, Charoenkiatkul S, "Inhibitory effects of spices and herbs on iron availability", Int J Food Sci Nutr. 2009;60 Suppl 1:43-55. doi: 10.1080/09637480802084844. Epub 2008 Jul 4. PMID: 18651292.. https://pubmed.ncbi.nlm.nih.gov/18651292/
  • 280. Jurenka JS, "Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research", Altern Med Rev. 2009 Jun;14(2):141-53. Erratum in: Altern Med Rev. 2009 Sep;14(3):277. PMID: 19594223.. https://pubmed.ncbi.nlm.nih.gov/19594223/
  • 281. Jakubczyk K, Drużga A, Katarzyna J, Skonieczna-Żydecka K, "Antioxidant Potential of Curcumin-A Meta-Analysis of Randomized Clinical Trials", Antioxidants (Basel). 2020 Nov 6;9(11):1092. doi: 10.3390/antiox9111092. PMID: 33172016; PMCID: PMC7694612.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694612/
  • 282. Prasad S, Aggarwal BB., "Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine", In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 13. https://www.ncbi.nlm.nih.gov/books/NBK92752/
  • 283. Vaughn AR, Branum A, Sivamani RK., "Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence", Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.. https://pubmed.ncbi.nlm.nih.gov/27213821/
  • 284. Liju VB, Jeena K, Kuttan R, "An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L", Indian J Pharmacol. 2011 Sep;43(5):526-31. doi: 10.4103/0253-7613.84961. PMID: 22021994; PMCID: PMC3195121.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195121/
  • 285. Peterson CT, Vaughn AR, Sharma V, Chopra D, Mills PJ, Peterson SN, Sivamani RK., "Effects of Turmeric and Curcumin Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study", J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18790725. doi: 10.1177/2515690X18790725. PMID: 30088420; PMCID: PMC6083746.. https://pubmed.ncbi.nlm.nih.gov/30088420/
  • 286. Vollono L, Falconi M, Gaziano R, Iacovelli F, Dika E, Terracciano C, Bianchi L, Campione E, "Potential of Curcumin in Skin Disorders", Nutrients. 2019 Sep 10;11(9):2169. doi: 10.3390/nu11092169. PMID: 31509968; PMCID: PMC6770633.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770633/
  • 287. Vaughn AR, Branum A, Sivamani RK., "Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence.", Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.. https://pubmed.ncbi.nlm.nih.gov/27213821/
  • 288. SU Zaman. N Akhtar, "Effect of Turmeric (Curcuma longa Zingiberaceae) Extract Cream on Human Skin Sebum Secretion", eISSN: 1596-9827; print ISSN: 1596-5996; Vol. 12 No. 5 (2013); DOI: 10.4314/tjpr.v12i5.1. https://www.ajol.info/index.php/tjpr/article/view/95928
  • 289. Vollono L, Falconi M, Gaziano R, Iacovelli F, Dika E, Terracciano C, Bianchi L, Campione E, "Potential of Curcumin in Skin Disorders", Nutrients. 2019 Sep 10;11(9):2169. doi: 10.3390/nu11092169. PMID: 31509968; PMCID: PMC6770633.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770633/
  • 290. Varma SR, Sivaprakasam TO, Mishra A, Prabhu S, M R, P R., "Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin", Eur J Pharmacol. 2017 Oct 15;813:33-41. doi: 10.1016/j.ejphar.2017.07.040. Epub 2017 Jul 21. PMID: 28736282.. https://pubmed.ncbi.nlm.nih.gov/28736282/
  • 291. Parichehr Bahraini PharmD, Mehdi Rajabi PhD, Parvin Mansouri MD, Golnaz Sarafian PharmD, Reza Chalangari MD, Zahra Azizian MD, "Turmeric tonic as a treatment in scalp psoriasis: A randomized placebo-control clinical trial", onlinelibrary.wiley.com. https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.12513
  • 292. Ibrahim, S., Amer, A., ElKashishy, K., Sami, D., Nofal, H., Abdellatif, A. (2022), "Turmeric extract based therapy for psoriasis", Zagazig University Medical Journal, 28(6.2), 164-170. doi: 10.21608/zumj.2020.20702.1648. https://zumj.journals.ekb.eg/article_68118.html
  • 293. Vollono L, Falconi M, Gaziano R, Iacovelli F, Dika E, Terracciano C, Bianchi L, Campione E, "Potential of Curcumin in Skin Disorders", Nutrients. 2019 Sep 10;11(9):2169. doi: 10.3390/nu11092169. PMID: 31509968; PMCID: PMC6770633. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770633/
  • 294. Peng Y, Ao M, Dong B, Jiang Y, Yu L, Chen Z, Hu C, Xu R, "Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures", Drug Des Devel Ther. 2021 Nov 2;15:4503-4525. doi: 10.2147/DDDT.S327378. PMID: 34754179; PMCID: PMC8572027. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572027/
  • 295. Dania Akbik, Maliheh Ghadiri, Wojciech Chrzanowski, Ramin Rohanizadeh, "Curcumin as a wound healing agent", Life Sciences, Volume 116, Issue 1, 2014, Pages 1-7, ISSN 0024-3205. https://www.sciencedirect.com/science/article/abs/pii/S0024320514007036
  • 296. Heng MC, "Signaling pathways targeted by curcumin in acute and chronic injury: burns and photo-damaged skin", Int J Dermatol. 2013 May;52(5):531-43. doi: 10.1111/j.1365-4632.2012.05703.x. Epub 2012 Dec 11. PMID: 23231506.. https://pubmed.ncbi.nlm.nih.gov/23231506/
  • 297. Barja G, "Free radicals and aging", Trends Neurosci. 2004 Oct;27(10):595-600. doi: 10.1016/j.tins.2004.07.005. PMID: 15374670.. https://pubmed.ncbi.nlm.nih.gov/15374670/
  • 298. Sumiyoshi M, Kimura Y, "Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice", Phytomedicine. 2009 Dec;16(12):1137-43. doi: 10.1016/j.phymed.2009.06.003. Epub 2009 Jul 4. PMID: 19577913.. https://pubmed.ncbi.nlm.nih.gov/19577913/
  • 299. Yegorov YE, Poznyak AV, Nikiforov NG, Sobenin IA, Orekhov AN, "The Link between Chronic Stress and Accelerated Aging", Biomedicines. 2020 Jul 7;8(7):198. doi: 10.3390/biomedicines8070198. PMID: 32645916; PMCID: PMC7400286.. https://pubmed.ncbi.nlm.nih.gov/32645916/
  • 300. Prasad S, Aggarwal BB, "Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine", In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 13. https://www.ncbi.nlm.nih.gov/books/NBK92752/
  • 301. Tonya Russell, "The Dark Side of Skin Lightening", consumerreports.org/. https://www.consumerreports.org/beauty-personal-care/the-dark-side-of-skin-lightening-a7690701735/
  • 302. Hollinger JC, Angra K, Halder RM, "Are Natural Ingredients Effective in the Management of Hyperpigmentation? A Systematic Review.", J Clin Aesthet Dermatol. 2018 Feb;11(2):28-37. Epub 2018 Feb 1. PMID: 29552273; PMCID: PMC5843359.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843359/
  • 303. Vaughn AR, Branum A, Sivamani RK., "Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence", Phytother Res. 2016 Aug;30(8):1243-64. doi: 10.1002/ptr.5640. Epub 2016 May 23. PMID: 27213821.. https://pubmed.ncbi.nlm.nih.gov/27213821/
  • 304. Klimek-Szczykutowicz M, Szopa A, Ekiert H, "Citrus limon (Lemon) Phenomenon-A Review of the Chemistry, Pharmacological Properties, Applications in the Modern Pharmaceutical, Food, and Cosmetics Industries, and Biotechnological Studies", Plants (Basel). 2020 Jan 17;9(1):119. doi: 10.3390/plants9010119. PMID: 31963590; PMCID: PMC7020168.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020168/
  • 305. Tyler Smith, Farhana Majid, Veronica Eckl, and Claire Morton Reynolds, "Herbal Supplement Sales in US Increase by Record-Breaking 17.3% in 2020", American Botanical Council; Austin, Texas SPINS; Chicago, Illinois Nutrition Business Journal; Boulder, Colorado. http://herbalgram.org/media/16783/hg131-hmr.pdf
  • 306. Sahdeo Prasad, Bharat B. Aggarwal, "Chapter 13Turmeric, the Golden Spice From Traditional Medicine to Modern Medicine", Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.. https://www.ncbi.nlm.nih.gov/books/NBK92752/
  • 308. Arunava Gantait, Tapu Barman, Pulok K Mukherjee, "Validated method for estimation of curcumin in turmeric powder", Research gate - Table 3 - uploaded by Tapu Barman. https://www.researchgate.net/figure/Percentages-of-curcumin-present-in-different-brands-of-turmeric-powder_tbl3_233726729
  • 309. Gustavo Barja, "Free radicals and aging", Affiliations PMID: 15374670 DOI: 10.1016/j.tins.2004.07.005. https://pubmed.ncbi.nlm.nih.gov/15374670/
  • 310. Dania Akbik, Maliheh Ghadiri, Wojciech Chrzanowski, Ramin Rohanizadeh, "Curcumin as a wound healing agent", Life Sciences Volume 116, Issue 1, 22 October 2014, Pages 1-7. https://www.sciencedirect.com/science/article/abs/pii/S0024320514007036
  • 311. SU Zaman, N Akhtar, "Effect of Turmeric (Curcuma longa Zingiberaceae) Extract Cream on Human Skin Sebum Secretion", Tropical Journal of Pharmaceutical Research Home / Archives / Vol. 12 No. 5 (2013) / Articles. https://www.ajol.info/index.php/tjpr/article/view/95928
  • 312. Sandeep R Varma, Thiyagarajan O Sivaprakasam, Abheepsa Mishra, Sunil Prabhu, Rafiq M, Rangesh P, "Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin", Eur J Pharmacol. 2017 Oct 15;813:33-41. doi: 10.1016/j.ejphar.2017.07.040. Epub 2017 Jul 21.. https://pubmed.ncbi.nlm.nih.gov/28736282/
  • 313. Madalene C Y Heng, "Signaling pathways targeted by curcumin in acute and chronic injury: burns and photo-damaged skin", Int J Dermatol. 2013 May;52(5):531-43. doi: 10.1111/j.1365-4632.2012.05703.x. Epub 2012 Dec 11.. https://pubmed.ncbi.nlm.nih.gov/23231506/
  • 314. Gustavo Barja, "Free radicals and aging", Trends Neurosci. 2004 Oct;27(10):595-600. doi: 10.1016/j.tins.2004.07.005.. https://pubmed.ncbi.nlm.nih.gov/15374670/
  • 315. Si Qin,1 Lifan Huang,1 Jiaojiao Gong,1,2 Shasha Shen,1,2 Juan Huang,1,2 Hong Ren,2 and Huaidong Hucorresponding author1,2, "Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials", Journal List Nutr J v.16; 2017 PMC5637251 Nutr J. 2017; 16: 68. Published online 2017 Oct 11. doi: 10.1186/s12937-017-0293-y. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637251/
  • 316. Cheng Li 1, Xiao Miao 2, Fengsheng Li 3, Binay Kumar Adhikari 1, Yucheng Liu 4, Jian Sun 1, Rong Zhang 3, Lu Cai 5, Quan Liu 1, Yonggang Wang 1, "Curcuminoids: Implication for inflammation and oxidative stress in cardiovascular diseases", Phytother Res. 2019 May;33(5):1302-1317. doi: 10.1002/ptr.6324. Epub 2019 Mar 4.. https://pubmed.ncbi.nlm.nih.gov/30834628/
  • 317. Hong Li 1, Antoni Sureda 2, Hari Prasad Devkota 3, Valeria Pittalà 4, Davide Barreca 5, Ana Sanches Silva 6, Devesh Tewari 7, Suowen Xu 8, Seyed Mohammad Nabavi 9, "Curcumin, the golden spice in treating cardiovascular diseases", Biotechnol Adv. 2020 Jan-Feb;38:107343. doi: 10.1016/j.biotechadv.2019.01.010. Epub 2019 Feb 1.. https://pubmed.ncbi.nlm.nih.gov/30716389/
  • 318. Peter G Bradford 1, "Curcumin and obesity", Biofactors. 2013 Jan-Feb;39(1):78-87. doi: 10.1002/biof.1074. Epub 2013 Jan 22.. https://pubmed.ncbi.nlm.nih.gov/23339049/
  • 319. Won-Yeong Song and Jeong-Hwa, "Korean Curcuma longa L. induces lipolysis and regulates leptin in adipocyte cells and rats", Nutr Res Pract. 2016 Oct; 10(5): 487–493. Published online 2016 Jul 29. doi: 10.4162/nrp.2016.10.5.487. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037065/
  • 320. Christine T Peterson 1, Alexandra R Vaughn 2 3, Vandana Sharma 4, Deepak Chopra 1 5, Paul J Mills 1, Scott N Peterson 4, Raja K Sivamani 2 6 7, "Effects of Turmeric and Curcumin Dietary Supplementation on Human Gut Microbiota: A Double-Blind, Randomized, Placebo-Controlled Pilot Study", J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18790725. doi: 10.1177/2515690X18790725.. https://pubmed.ncbi.nlm.nih.gov/30088420/
  • 321. Soheil Zorofchian Moghadamtousi 1, Habsah Abdul Kadir 1, Pouya Hassandarvish 2, Hassan Tajik 3, Sazaly Abubakar 2, Keivan Zandi 4, "A review on antibacterial, antiviral, and antifungal activity of curcumin", Biomed Res Int. 2014;2014:186864. doi: 10.1155/2014/186864. Epub 2014 Apr 29.. https://pubmed.ncbi.nlm.nih.gov/24877064/
  • 322. Eleonora Hay 1, Angela Lucariello 2, Marcella Contieri 1, Teresa Esposito 3, Antonio De Luca 1, Germano Guerra 4, Angelica Perna 5, "Therapeutic effects of turmeric in several diseases: An overview", Chem Biol Interact. 2019 Sep 1;310:108729. doi: 10.1016/j.cbi.2019.108729. Epub 2019 Jun 27.. https://pubmed.ncbi.nlm.nih.gov/31255636/
  • 323. N. Maithili Karpaga Selvi, M. G. Sridhar,corresponding author R. P. Swaminathan, and R. Sripradha, "Efficacy of Turmeric as Adjuvant Therapy in Type 2 Diabetic Patients", Indian J Clin Biochem. 2015 Apr; 30(2): 180–186. Published online 2014 May 8. doi: 10.1007/s12291-014-0436-2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393385/
  • 324. Dong-wei Zhang, 1 ,* Min Fu, 2 Si-Hua Gao, 1 and Jun-Li Liu 2 ,*, "Curcumin and Diabetes: A Systematic Review", Evid Based Complement Alternat Med. 2013; 2013: 636053. Published online 2013 Nov 24. doi: 10.1155/2013/636053. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857752/
  • 325. Dhaneshwar Shep,corresponding author1 Chitra Khanwelkar,1 Prakashchandra Gade,2 and Satyanand Karad3, "Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study", Trials. 2019; 20: 214. Published online 2019 Apr 11. doi: 10.1186/s13063-019-3327-2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460672/
  • 326. Zhiqiang Wang, MPharm, Graeme Jones, PhD, Tania Winzenberg, PhD, "Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis", Annals of Internal Medicine Original Research1 December 2020. https://www.acpjournals.org/doi/10.7326/M20-0990
  • 327. Gonzalo Flores, Ph.D.*, "Curcuma longa L. extract improves the cortical neural connectivity during the aging process", Journal List Neural Regen Res v.12(6); 2017 Jun PMC5514855. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514855/
  • 328. Joerg Hucklenbroich 1 2, Rebecca Klein 3 4, Bernd Neumaier 5, Rudolf Graf 6, Gereon Rudolf Fink 7 8, Michael Schroeter 9 10 11, Maria Adele Rueger 12 13 14, "Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo", Stem Cell Res Ther. 2014 Sep 26;5(4):100. doi: 10.1186/scrt500.. https://pubmed.ncbi.nlm.nih.gov/25928248/
  • 329. Ciqiong Chen, Li Long, Fusheng Zhang, Qin Chen, Cheng Chen, Xiaorui Yu, Qingya Liu, Jinku Bao, Zhangfu Long, "Antifungal activity, main active components and mechanism of Curcuma longa extract against Fusarium graminearum", Journal List PLoS One PMC5854386 PLoS One. 2018; 13(3): e0194284. Published online 2018 Mar 15. doi: 10.1371/journal.pone.0194284. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854386/
  • 330. Laura E. Wright,1 Jennifer B. Frye,1 Barbara N. Timmermann,2 and Janet L. Funk1,*, "Protection of Trabecular Bone in Ovariectomized Rats by Turmeric (Curcuma longa L.) is Dependent on Extract Composition", Journal List HHS Author Manuscripts PMC2945868 J Agric Food Chem. Author manuscript; available in PMC 2011 Sep 8. Published in final edited form as: J Agric Food Chem. 2010 Sep 8; 58(17): 9498–9504. doi: 10.1021/jf101873f. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945868/
  • 331. Julie S Jurenka 1, "Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research", Altern Med Rev. 2009 Jun;14(2):141-53.. https://pubmed.ncbi.nlm.nih.gov/19594223/
  • 332. Susan J. Hewlings1,2,* and Douglas S. Kalman3,4, "Curcumin: A Review of Its’ Effects on Human Health", Journal List Foods PMC5664031 Foods. 2017 Oct; 6(10): 92. Published online 2017 Oct 22. doi: 10.3390/foods6100092. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
  • 333. Suruchi Mishra, Ph.D., Bryan Stierman, M.D., M.P.H., Jaime J. Gahche, Ph.D., M.P.H., and Nancy Potischman, Ph.D., "Dietary Supplement Use Among Adults: United States, 2017–2018", NCHS Data Brief No. 399, February 2021. https://www.cdc.gov/nchs/products/databriefs/db399.htm
  • 334. National Center for Complementary and Integrative Health, "Astragalus", Home Health Information Astragalus. https://www.nccih.nih.gov/health/astragalus
  • 335. Yijun Zheng,1 Weiyu Ren,2 Lina Zhang,3 Yuemei Zhang,4 Dongling Liu,1,2,* and Yongqi Liu1,, "A Review of the Pharmacological Action of Astragalus Polysaccharide", Front Pharmacol. 2020; 11: 349. Published online 2020 Mar 24. doi: 10.3389/fphar.2020.00349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105737/
  • 336. Yijun Zheng,1 Weiyu Ren,2 Lina Zhang,3 Yuemei Zhang,4 Dongling Liu,1,2,* and Yongqi Liu1,, "A Review of the Pharmacological Action of Astragalus Polysaccharide", Front Pharmacol. 2020; 11: 349. Published online 2020 Mar 24. doi: 10.3389/fphar.2020.00349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105737/
  • 337. Jun-Ming Zhang, MSc, MD1 and Jianxiong An, MSc, MD, "Cytokines, Inflammation and Pain", Int Anesthesiol Clin. Author manuscript; available in PMC 2009 Nov 30. Published in final edited form as: Int Anesthesiol Clin. 2007 Spring; 45(2): 27–37. doi: 10.1097/AIA.0b013e318034194e. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785020/
  • 338. Charles Patrick Davis, MD, PhD, "Medical Definition of Immunoglobulin", medterms medical dictionary a-z list / immunoglobulin definition. https://www.medicinenet.com/immunoglobulin/definition.htm
  • 339. National Center for Chronic Disease Prevention and Health Promotion , Division for Heart Disease and Stroke Prevention, "Heart Disease Facts", CDC - Heart Disease Home - Heart Disease Statistics and Maps. https://www.cdc.gov/heartdisease/facts.htm
  • 340. National Center for Chronic Disease Prevention and Health Promotion , Division for Heart Disease and Stroke Prevention, "Prevent Heart Disease", CDC - Heart Disease Home. https://www.cdc.gov/heartdisease/prevention.htm
  • 341. Dr. Choi et al., 2021, "This Plant-Based Diet Reduces Heart Disease Risk 50%", Published: January 8, 2023 in category: Heart Disease. https://www.spring.org.uk/2023/01/plant-based.php
  • 342. Zheng, Ren, Zhang, Zhang, Liu and Liu, "Figure 1", Front Pharmacol. 2020; 11: 349. Published online 2020 Mar 24. doi: 10.3389/fphar.2020.00349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105737/figure/f1/
  • 343. Rx Lists, "ASTRAGALUS", VITAMINS, HERBS, DIETARY SUPPLEMENTS A-Z LIST. https://www.rxlist.com/astragalus/supplements.htm
  • 344. Jingxuan Zhou,1,† Nanhai Zhang,1,† Liang Zhao,2 Wei Wu,3 Liebing Zhang,1 Feng Zhou,1,* and Jingming Li4,* Barry J. Parsons, Academic Editor, "Astragalus Polysaccharides and Saponins Alleviate Liver Injury and Regulate Gut Microbiota in Alcohol Liver Disease Mice", Foods. 2021 Nov; 10(11): 2688. Published online 2021 Nov 3. doi: 10.3390/foods10112688. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8623381/
  • 345. Wen Liu 1, Fang-Fang Gao, Qun Li, Jia-Wei Lv, Ying Wang, Peng-Chao Hu, Qing-Ming Xiang, Lei Wei, "Protective effect of astragalus polysaccharides on liver injury induced by several different chemotherapeutics in mice", Asian Pac J Cancer Prev. 2014;15(23):10413-20. doi: 10.7314/apjcp.2014.15.23.10413.. https://pubmed.ncbi.nlm.nih.gov/25556485/
  • 347. The National Heart, Lung, and Blood Institute, "What Is Metabolic Syndrome?", Home > Metabolic Syndrome. https://www.nhlbi.nih.gov/health/metabolic-syndrome
  • 348. Diabetes Education Online Diabetes Teaching Center at the University of California, San Francisco, "The Liver & Blood Sugar", Home » Types Of Diabetes » Type 1 Diabetes » Understanding Type 1 Diabetes » How The Body Processes Sugar » The Liver & Blood Sugar. https://dtc.ucsf.edu/types-of-diabetes/type1/understanding-type-1-diabetes/how-the-body-processes-sugar/the-liver-blood-sugar/
  • 349. Diabetes Education Online Diabetes Teaching Center at the University of California, San Francisco, "Blood Sugar & Stress", Home » Types Of Diabetes » Type 2 Diabetes » Understanding Type 2 Diabetes » How The Body Processes Sugar » Blood Sugar & Stress. https://dtc.ucsf.edu/types-of-diabetes/type2/understanding-type-2-diabetes/how-the-body-processes-sugar/blood-sugar-stress/
  • 350. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), "Kidney Disease Statistics for the United States", Home / Health Information / Health Statistics / Kidney Disease Statistics for the United States. https://www.niddk.nih.gov/health-information/health-statistics/kidney-disease
  • 351. Jie Sun, Shanzhai Wei, Yilai Zhang, and Jia Li, "Protective Effects of Astragalus Polysaccharide on Sepsis-Induced Acute Kidney Injury", Journal List Anal Cell Pathol (Amst) v.2021; 2021 PMC7857912. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857912/
  • 352. Qing Ma, 1 Yao Xu, 1 Lumin Tang, 1 Xiaoqian Yang, 1 Zhejun Chen, 1 Yuehan Wei, 1 Xinghua Shao, 1 Xiaoguang Shao, 2 Zhixiang Xin, 2 Biao Cai, 2 Qi Wang, and Shan Mou, "Astragalus Polysaccharide Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Oxidative Damage and Mitochondrial Dysfunction", Biomed Res Int. 2020; 2020: 2851349. Published online 2020 Jan 3. doi: 10.1155/2020/2851349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970487/
  • 353. Jinxia Li, Lu Xu, Rui Sang, Yifan Yu, Bingjie Ge, Xuemei Zhang, "Immunomodulatory and anti-inflammatory effects of total flavonoids of Astragalus by regulating NF-ΚB and MAPK signalling pathways in RAW 264.7 macrophages", Pharmazie. 2018 Oct 1;73(10):589-593. doi: 10.1691/ph.2018.8633.. https://pubmed.ncbi.nlm.nih.gov/30223923/
  • 354. Xi Chen 1, Li-Hua Peng, Ni Li, Qi-Mei Li, Ping Li, Kwok-Pui Fung, Ping-Chung Leung, Jian-Qing Gao, "The healing and anti-scar effects of astragaloside IV on the wound repair in vitro and in vivo", J Ethnopharmacol. 2012 Feb 15;139(3):721-7. doi: 10.1016/j.jep.2011.11.035. Epub 2011 Nov 28.. https://pubmed.ncbi.nlm.nih.gov/22143155/
  • 346. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), "Diabetes Statistics", Home Health Information Health Statistics Diabetes Statistics. https://www.niddk.nih.gov/health-information/health-statistics/diabetes-statistics
  • 355. American Thyroid Association, "Prevalence and Impact of Thyroid Disease", Home » Media » General Information/Press Room. https://www.thyroid.org/media-main/press-room/
  • 356. Cleveland Clinic medical professional, "Thyroid", Cleveland Clinic medical professional - Health Library / Body Systems & Organs. https://my.clevelandclinic.org/health/body/23188-thyroid
  • 357. Sima Nazarpour 1, Fahimeh Ramezani Tehrani 2, Masoumeh Simbar 1, Fereidoun Azizi 3, "Thyroid dysfunction and pregnancy outcomes", Review Iran J Reprod Med. 2015 Jul;13(7):387-96.. https://pubmed.ncbi.nlm.nih.gov/26494985/
  • 358. Ashok Kumar Sharma 1, Indraneel Basu 1, Siddarth Singh 1, "Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial", Randomized Controlled Trial J Altern Complement Med. 2018 Mar;24(3):243-248.. https://pubmed.ncbi.nlm.nih.gov/28829155/
  • 359. Mary Ann C. Stephens, Ph.D., "Stress and the HPA Axis", Journal List Alcohol Res v.34(4); 2012 PMC3860380. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860380/
  • 360. G Benker 1, M Raida, T Olbricht, R Wagner, W Reinhardt, D Reinwein, "TSH secretion in Cushing's syndrome: relation to glucocorticoid excess, diabetes, goitre, and the 'sick euthyroid syndrome'", Clin Endocrinol (Oxf). 1990 Dec;33(6):777-86. doi: 10.1111/j.1365-2265.1990.tb03915.x.. https://pubmed.ncbi.nlm.nih.gov/2128925/
  • 361. Salam Ranabir, Reetu Keisam JNIMS, "Stress and hormones", PubMed March 2011 DOI:10.4103/2230-8210.77573. https://www.researchgate.net/publication/51138476_Stress_and_hormones
  • 362. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Journal List Medicine (Baltimore) v.98(37); 2019 Sep PMC6750292. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R18
  • 363. Danielle Pacheco, Staff Writer, Dr. Abhinav Singh, Sleep Physician, "Thyroid Issues and Sleep", Home / Physical Health and Sleep / Thyroid Issues and Sleep. https://www.sleepfoundation.org/physical-health/thyroid-issues-and-sleep
  • 364. Hamide Ashraf, 1 , 2 Mojtaba Heydari, 2 Mesbah Shams, 3 Mohammad Mehdi Zarshenas, 4 , 5 , 6 Ali Tavakoli, 1 , 2 and Mehrab Sayadi 7, "Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial", Journal List Evid Based Complement Alternat Med v.2022; 2022 PMC8794674. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794674/
  • 365. Nguyen Hoang Anh,1 Sun Jo Kim,1 Nguyen Phuoc Long,1 Jung Eun Min,1 Young Cheol Yoon,1 Eun Goo Lee,1 Mina Kim,1 Tae Joon Kim,1 Yoon Young Yang,1 Eui Young Son,1 Sang Jun Yoon,1 Nguyen Co Diem,2 Hyung Min Kim,1 and Sung Won Kwon1,*, "Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials", Journal List Nutrients PMC7019938. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019938/
  • 366. Javid Ghazizadeh 1 2 3, Saeed Sadigh-Eteghad 1, Wolfgang Marx 4, Ali Fakhari 5, Sanaz Hamedeyazdan 6, Mohammadali Torbati 7, Somaiyeh Taheri-Tarighi 1, Mostafa Araj-Khodaei 2 8, Mojgan Mirghafourvand 9, "The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis", Review Phytother Res. 2021 Dec;35(12):6690-6705. doi: 10.1002/ptr.7252. Epub 2021 Aug 27.. https://pubmed.ncbi.nlm.nih.gov/34449930/
  • 367. Andrew Scholey 1, Amy Gibbs 2, Chris Neale 3, Naomi Perry 4, Anastasia Ossoukhova 5, Vanessa Bilog 6, Marni Kras 7, Claudia Scholz 8, Mathias Sass 9, Sybille Buchwald-Werner 10, "Anti-stress effects of lemon balm-containing foods", Randomized Controlled Trial Nutrients. 2014 Oct 30;6(11):4805-21. doi: 10.3390/nu6114805.. https://pubmed.ncbi.nlm.nih.gov/25360512/
  • 368. David O Kennedy 1, Wendy Little, Andrew B Scholey, "Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)", Clinical Trial Psychosom Med. 2004 Jul-Aug;66(4):607-13. doi: 10.1097/01.psy.0000132877.72833.71.. https://pubmed.ncbi.nlm.nih.gov/15272110/
  • 369. Ali Zarei 1, Saeed Changizi-Ashtiyani 2, Soheila Taheri 3, Nasser Hosseini 4, "A Brief Overview of the Effects of Melissa officinalis L. Extract on the Function of Various Body Organs", Zahedan Journal of Research in Medical Sciences: Vol.17, issue 7. https://brieflands.com/articles/zjrms-1007.html#A1007REF26
  • 370. Ali Zarei, Saeed Changizi-Ashtiyani, R.A. Sokhandani, "The comparison of the alcholic extract effects of Mellissia officinalis and Atorvastatin on the serum levels of thyroid hormones in hypercholesterolemic male Rats", Home/ Internal Medicine/ Endocrinology/ Medicine/ Hormones/ Thyroid Hormones. https://www.researchgate.net/publication/289541515_The_comparison_of_the_alcholic_extract_effects_of_Mellissia_officinalis_and_Atorvastatin_on_the_serum_levels_of_thyroid_hormones_in_hypercholesterolemic_male_Rats
  • 371. Javid Ghazizadeh 1 2 3, Saeed Sadigh-Eteghad 1, Wolfgang Marx 4, Ali Fakhari 5, Sanaz Hamedeyazdan 6, Mohammadali Torbati 7, Somaiyeh Taheri-Tarighi 1, Mostafa Araj-Khodaei 2 8, Mojgan Mirghafourvand 9, "The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis", Review Phytother Res. 2021 Dec;35(12):6690-6705. doi: 10.1002/ptr.7252. Epub 2021 Aug 27.. https://pubmed.ncbi.nlm.nih.gov/34449930/
  • 372. Abolfazl Shakeri 1, Amirhossein Sahebkar 2, Behjat Javadi 3, "Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology", Review J Ethnopharmacol. 2016 Jul 21;188:204-28. doi: 10.1016/j.jep.2016.05.010.. https://pubmed.ncbi.nlm.nih.gov/27167460/
  • 373. Shiqi Huang 1, Dongdong Zhang 1, Yuze Li 1, Hao Fan 1, Yuanyuan Liu 1, Wenli Huang 1, Chong Deng 1, Wei Wang 1, Xiaomei Song 1, "Schisandra sphenanthera: A Comprehensive Review of its Botany, Phytochemistry, Pharmacology, and Clinical Applications", Review Am J Chin Med. 2021;49(7):1577-1622. doi: 10.1142/S0192415X21500749. Epub 2021 Sep 23.. https://pubmed.ncbi.nlm.nih.gov/34559620/
  • 374. Ni Cheng 1, Naiyan Ren, Hui Gao, Xingsheng Lei, Jianbin Zheng, Wei Cao, "Antioxidant and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4-induced acute liver damage in mice", Food Chem Toxicol. 2013 May;55:234-40. doi: 10.1016/j.fct.2012.11.022. Epub 2012 Nov 28.. https://pubmed.ncbi.nlm.nih.gov/23201450/
  • 375. Shiqi Huang 1, Dongdong Zhang 1, Yuze Li 1, Hao Fan 1, Yuanyuan Liu 1, Wenli Huang 1, Chong Deng 1, Wei Wang 1, Xiaomei Song 1, "Schisandra sphenanthera: A Comprehensive Review of its Botany, Phytochemistry, Pharmacology, and Clinical Applications", Review Am J Chin Med. 2021;49(7):1577-1622. doi: 10.1142/S0192415X21500749. Epub 2021 Sep 23.. https://pubmed.ncbi.nlm.nih.gov/34559620/
  • 376. Michal Rybnikář, Karel Šmejkal, Milan Žemlička, "Schisandra chinensis and its phytotherapeutical applications", Review Ceska Slov Farm. 2019 Summer;68(3):95-118.. https://pubmed.ncbi.nlm.nih.gov/31431019/
  • 377. Alexander Panossian 1, Georg Wikman, "Pharmacology of Schisandra chinensis Bail.: an overview of Russian research and uses in medicine", Review J Ethnopharmacol. 2008 Jul 23;118(2):183-212. doi: 10.1016/j.jep.2008.04.020. Epub 2008 Apr 24.. https://pubmed.ncbi.nlm.nih.gov/18515024/
  • 378. Carolyn M. Gallagherab, Jaymie R. Melikerbc, "Mercury and thyroid autoantibodies in U.S. women, NHANES 2007–2008", Environment International Volume 40, April 2012, Pages 39-43. https://www.sciencedirect.com/science/article/pii/S0160412011002716
  • 379. Shahad Imad, "Comparative Study between a Combination of Plants Extracts and Drugs on Thyroid Hormones and Lipid Profile in Experimental Animals", ResearchGate Home Shahad Imad. https://www.researchgate.net/profile/Shahad-Imad-2
  • 380. Deepak Langade,1 Subodh Kanchi, corresponding author2 Jaising Salve,3 Khokan Debnath,4 and Dhruv Ambegaokar5, "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study", Journal List Cureus v.11(9); 2019 Sep PMC6827862. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827862/
  • 381. Mohammad Hossein Mirjalili 1, Elisabeth Moyano, Mercedes Bonfill, Rosa M Cusido, Javier Palazón, "Steroidal lactones from Withania somnifera, an ancient plant for novel medicine", Review Molecules. 2009 Jul 3;14(7):2373-93. doi: 10.3390/molecules14072373.. https://pubmed.ncbi.nlm.nih.gov/19633611/
  • 382. L C Mishra 1, B B Singh, S Dagenais, "Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review", Review Altern Med Rev. 2000 Aug;5(4):334-46.. https://pubmed.ncbi.nlm.nih.gov/10956379/
  • 383. Shruti B. Patel,a Nirav J. Rao,a and Lal L. Hingoranib,∗, "Safety assessment of Withania somnifera extract standardized for Withaferin A: Acute and sub-acute toxicity study", Journal List J Ayurveda Integr Med v.7(1); 2016 Mar PMC4910650. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910650/
  • 384. Neeraj Tandon 1, Satyapal Singh Yadav 2, "Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments", J Ethnopharmacol. 2020 Jun 12;255:112768. doi: 10.1016/j.jep.2020.112768. Epub 2020 Mar 19.. https://pubmed.ncbi.nlm.nih.gov/32201301/
  • 385. John P. Cunha, DO, FACOEP, "ASHWAGANDHA", RXList CONSUMER_ASHWAGANDHA. https://www.rxlist.com/adhd_slideshow_parenting_tips/article.htm
  • 386. Drugs.com, "Ashwagandha", Medically reviewed by Drugs.com. Last updated on Dec 13, 2021.. https://www.drugs.com/npp/ashwagandha.html
  • 387. Deepak Langade 1, Subodh Kanchi 2, Jaising Salve 3, Khokan Debnath 4, Dhruv Ambegaokar 5, "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study", Cureus. 2019 Sep 28;11(9):e5797. doi: 10.7759/cureus.5797.. https://pubmed.ncbi.nlm.nih.gov/31728244/
  • 388. Biswajit Auddy, PhD1*; Jayaram Hazra, PhD2; Achintya Mitra, MD2; Bruce Abedon, PhD3; Shibnath Ghosal, PhD1, "A Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study", 1. Research and Development Center, Natreon Inc., Salt Lake City, Kolkata, India 2. Central Research Institute (Ayurveda), Ministry of Health and Family Welfare, Govt. of India, Bidhan Nagar, Kolkata, India 3. Director of Scientific Affairs, NutraGenesis LLC, Brattleboro, Vermont. https://blog.priceplow.com/wp-content/uploads/2014/08/withania_review.pdf
  • 389. K Chandrasekhar 1, Jyoti Kapoor, Sridhar Anishetty, "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022.. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 390. Deepak Langade 1, Vaishali Thakare 2, Subodh Kanchi 3, Sunil Kelgane 4, "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", Randomized Controlled Trial J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 391. Abhijit Deshpandea, Nushafreen Irania, Ratna BalkrishnanaIrin, Rosanna Bennyb, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Medicine Volume 72, August 2020, Pages 28-36. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 392. Mahesh K. Kaushik ,Sunil C. Kaul, Renu Wadhwa, Masashi Yanagisawa, Yoshihiro Urade, "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172508. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508
  • 393. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Journal List Medicine (Baltimore) v.98(37); 2019 Sep PMC6750292. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 394. Mahesh K. Kaushik ,Sunil C. Kaul, Renu Wadhwa, Masashi Yanagisawa, Yoshihiro Urade, "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172508. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508
  • 395. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Journal List Medicine (Baltimore) v.98(37); 2019 Sep PMC6750292. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 396. Nicolas C. Nicolaides 1, Alexandros N. Vgontzas 2, Ilia Kritikou 3, George Chrousos 4 Kenneth R Feingold 1, Bradley Anawalt 2, Alison Boyce 3, George Chrousos 4, Wouter W de Herder 5, Ketan Dhatariya 6, Kathleen Dungan 7, Jerome M Hershman 8, Johannes Hofland 9, Sanjay Kalra 10, Gregory Kaltsas 11, Christian Koch 12, Peter Kopp 13, Márta Korbonits 14, Christopher S Kovacs 15, Wendy Kuohung 16, Blandine Laferrère 17, Miles Levy 18, Elizabeth A McGee 19, Robert McLachlan 20, John E Morley 21, Maria New 22, Jonathan Purnell 23, Rakesh Sahay 24, Frederick Singer 25, Mark A Sperling 26, Constantine A Stratakis 27, Dace L Trence 28, Don P Wilson 29 , editors., "HPA Axis and Sleep", In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. 2020 Nov 24.. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 397. Eva Fries 1, Lucia Dettenborn, Clemens Kirschbaum, "The cortisol awakening response (CAR): facts and future directions", Review Int J Psychophysiol . 2009 Apr;72(1):67-73. doi: 10.1016/j.ijpsycho.2008.03.014.. https://pubmed.ncbi.nlm.nih.gov/18854200/
  • 398. Nicolas C. Nicolaides 1, Alexandros N. Vgontzas 2, Ilia Kritikou 3, George Chrousos 4 Kenneth R Feingold 1, Bradley Anawalt 2, Alison Boyce 3, George Chrousos 4, Wouter W de Herder 5, Ketan Dhatariya 6, Kathleen Dungan 7, Jerome M Hershman 8, Johannes Hofland 9, Sanjay Kalra 10, Gregory Kaltsas 11, Christian Koch 12, Peter Kopp 13, Márta Korbonits 14, Christopher S Kovacs 15, Wendy Kuohung 16, Blandine Laferrère 17, Miles Levy 18, Elizabeth A McGee 19, Robert McLachlan 20, John E Morley 21, Maria New 22, Jonathan Purnell 23, Rakesh Sahay 24, Frederick Singer 25, Mark A Sperling 26, Constantine A Stratakis 27, Dace L Trence 28, Don P Wilson 29, "HPA Axis and Sleep", In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000. 2020 Nov 24.. https://pubmed.ncbi.nlm.nih.gov/25905298/
  • 399. Diego A. Bonilla,1,2,3,4,* Yurany Moreno,1,2 Camila Gho,1 Jorge L. Petro,1,3 Adrián Odriozola-Martínez,4,5,6 and Richard B. Kreider7, "Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis", Journal List J Funct Morphol Kinesiol PMC8006238. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006238/
  • 400. World Health Organization, "Headache disorders: How common are headaches?", Home/Newsroom/Questions and answers/Headache disorders: How common are headaches?. https://www.who.int/news-room/questions-and-answers/item/headache-disorders-how-common-are-headaches
  • 401. Drugs.com, "Medications for Headache", Treatments | Pain. https://www.drugs.com/condition/headache.html
  • 402. Harvard Health Publishing Harvard Medical School, "Causes of common headaches", By Heidi Godman Executive Editor, Harvard Health Letter February 3, 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138407
  • 403. R P Silva-Néto 1, M F P Peres, M M Valença, "Odorant substances that trigger headaches in migraine patients", Cephalalgia. 2014 Jan;34(1):14-21. doi: 10.1177/0333102413495969. Epub 2013 Jul 5.. https://pubmed.ncbi.nlm.nih.gov/23832131/
  • 404. Anil Pareek 1, Manish Suthar, Garvendra S Rathore, Vijay Bansal, "Feverfew (Tanacetum parthenium L.): A systematic review", Pharmacogn Rev. 2011 Jan;5(9):103-10. doi: 10.4103/0973-7847.79105.. https://pubmed.ncbi.nlm.nih.gov/22096324/
  • 405. National Institutes of Health, "Feverfew", Home - Health Information - Feverfew. https://www.nccih.nih.gov/health/feverfew
  • 406. Anil Pareek 1, Manish Suthar, Garvendra S Rathore, Vijay Bansal, "Feverfew (Tanacetum parthenium L.): A systematic review", Pharmacogn Rev. 2011 Jan;5(9):103-10. doi: 10.4103/0973-7847.79105.. https://pubmed.ncbi.nlm.nih.gov/22096324/
  • 407. Serena Materazzi 1, Silvia Benemei, Camilla Fusi, Roberta Gualdani, Gaetano De Siena, Nisha Vastani, David A Andersson, Gabriela Trevisan, Maria Rosa Moncelli, Xiaomei Wei, Gregory Dussor, Federica Pollastro, Riccardo Patacchini, Giovanni Appendino, Pierangelo Geppetti, Romina Nassini, "Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel", Pain. 2013 Dec;154(12):2750-2758. doi: 10.1016/j.pain.2013.08.002. Epub 2013 Aug 8.. https://pubmed.ncbi.nlm.nih.gov/23933184/
  • 408. E Ernst 1, M H Pittler, "The efficacy and safety of feverfew (Tanacetum parthenium L.): an update of a systematic review", Review Public Health Nutr. 2000 Dec;3(4A):509-14. doi: 10.1017/s1368980000000598.. https://pubmed.ncbi.nlm.nih.gov/11276299/
  • 409. Barbara Wider 1, Max H Pittler, Edzard Ernst, "Feverfew for preventing migraine", Cochrane Database Syst Rev. 2015 Apr 20;4(4):CD002286. doi: 10.1002/14651858.CD002286.pub3.. https://pubmed.ncbi.nlm.nih.gov/25892430/
  • 410. R Shrivastava 1, J C Pechadre, G W John, "Tanacetum parthenium and Salix alba (Mig-RL) combination in migraine prophylaxis: a prospective, open-label study", Clinical Trial Clin Drug Investig. 2006;26(5):287-96. doi: 10.2165/00044011-200626050-00006.. https://pubmed.ncbi.nlm.nih.gov/17163262/
  • 411. Sahdeo Prasad, Bharat B. Aggarwal Iris F. F. Benzie, Sissi Wachtel-Galor, "Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine", In: Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 13.. https://pubmed.ncbi.nlm.nih.gov/22593922/
  • 412. Venugopal P Menon 1, Adluri Ram Sudheer, "Antioxidant and anti-inflammatory properties of curcumin", Review Adv Exp Med Biol. 2007;595:105-25. doi: 10.1007/978-0-387-46401-5_3.. https://pubmed.ncbi.nlm.nih.gov/17569207/
  • 413. Andrew F Russo 1, "Calcitonin gene-related peptide (CGRP): a new target for migraine", Review Annu Rev Pharmacol Toxicol. 2015;55:533-52. doi: 10.1146/annurev-pharmtox-010814-124701. Epub 2014 Oct 8.. https://pubmed.ncbi.nlm.nih.gov/25340934/
  • 414. J Peter H Burbach 1, "What are neuropeptides?", Methods Mol Biol. 2011;789:1-36. doi: 10.1007/978-1-61779-310-3_1.. https://pubmed.ncbi.nlm.nih.gov/21922398/
  • 415. Peter Uciechowski 1, Wolfram C M Dempke 2, "Interleukin-6: A Masterplayer in the Cytokine Network", Review Oncology. 2020;98(3):131-137. doi: 10.1159/000505099. Epub 2020 Jan 20.. https://pubmed.ncbi.nlm.nih.gov/31958792/
  • 416. Adriana E. Bulboacă, 1 Sorana D. Bolboacă,corresponding author 2 Ioana C. Stănescu, 3 Carmen A. Sfrângeu, 1 and Angelo C. Bulboacă 3, "Preemptive Analgesic and Antioxidative Effect of Curcumin for Experimental Migraine", Journal List Biomed Res Int PMC5674483. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674483/
  • 417. Adrian L Lopresti 1 2, Stephen J Smith 1 2, Peter D Drummond 2, "Herbal treatments for migraine: A systematic review of randomised-controlled studies", Phytother Res. 2020 Oct;34(10):2493-2517. doi: 10.1002/ptr.6701. Epub 2020 Apr 20.. https://pubmed.ncbi.nlm.nih.gov/32310327/
  • 418. Sahdeo Prasad and Bharat B. Aggarwal., "Chapter 13 Turmeric, the Golden Spice", From Traditional Medicine to Modern Medicine Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.. https://www.ncbi.nlm.nih.gov/books/NBK92752/
  • 419. M. Z. Siddiqui*, "Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview", Journal List Indian J Pharm Sci v.73(3); May-Jun 2011 PMC3309643. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309643/#ref21
  • 420. U Dahmen 1, Y L Gu, O Dirsch, L M Fan, J Li, K Shen, C E Broelsch, "Boswellic acid, a potent antiinflammatory drug, inhibits rejection to the same extent as high dose steroids", Transplant Proc. 2001 Feb-Mar;33(1-2):539-41. doi: 10.1016/s0041-1345(00)02131-x.. https://pubmed.ncbi.nlm.nih.gov/11266947/
  • 421. Raveendhara R. Bannuru, MD, PhD,1,2 Mikala C. Osani, BA,2 Fatimah Al-Eid, MD,2 and Chenchen Wang, MD, MSc1, "Efficacy of Curcumin and Boswellia for Knee Osteoarthritis: Systematic Review and Meta-Analysis", Journal List HHS Author Manuscripts PMC6131088. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131088/
  • 422. Christian Lampl 1, Bernhard Haider, Christine Schweiger, "Long-term efficacy of Boswellia serrata in four patients with chronic cluster headache", Case Reports Cephalalgia. 2012 Jul;32(9):719-22. doi: 10.1177/0333102412451357.. https://pubmed.ncbi.nlm.nih.gov/22767962/
  • 423. Cleveland Clinic, "Neuropathic Pain", Home / Health Library / Disease & Conditions. https://my.clevelandclinic.org/health/diseases/15833-neuropathic-pain
  • 424. L Jasmin 1, M V Wu, P T Ohara, "GABA puts a stop to pain", Review Curr Drug Targets CNS Neurol Disord. 2004 Dec;3(6):487-505. doi: 10.2174/1568007043336716.. https://pubmed.ncbi.nlm.nih.gov/15578966/
  • 425. A Ngan 1, R Conduit, "A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality", Randomized Controlled Trial Phytother Res. 2011 Aug;25(8):1153-9. doi: 10.1002/ptr.3400. Epub 2011 Feb 3.. https://pubmed.ncbi.nlm.nih.gov/21294203/
  • 426. Fariba Fahami, MSc,* Zahra Asali, MSc,* Abolfazl Aslani, PhD,** and Nahid Fathizadeh, MSc***, "A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers", Journal List Iran J Nurs Midwifery Res v.15(4); Autumn 2010 PMC3203277. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203277/
  • 427. Janmejai K Srivastava,1,2,* Eswar Shankar,1,2 and Sanjay Gupta1,2,3, "Chamomile: A herbal medicine of the past with bright future", Journal List HHS Author Manuscripts PMC2995283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995283/
  • 428. Adrian L Lopresti 1 2, Stephen J Smith 1 2, Peter D Drummond 2, "Herbal treatments for migraine: A systematic review of randomised-controlled studies", Phytother Res. 2020 Oct;34(10):2493-2517. doi: 10.1002/ptr.6701. Epub 2020 Apr 20.. https://pubmed.ncbi.nlm.nih.gov/32310327/
  • 429. Arman Zargaran 1 2, Afshin Borhani-Haghighi 3 4, Mohammad Salehi-Marzijarani 5, Pouya Faridi 6, Saeid Daneshamouz 7, Amir Azadi 7, Hossein Sadeghpour 8, Amirhossein Sakhteman 8, Abdolali Mohagheghzadeh 9 10, "Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study", Randomized Controlled Trial Neurol Sci. 2018 Aug;39(8):1345-1353. doi: 10.1007/s10072-018-3415-1. Epub 2018 May 28.. https://pubmed.ncbi.nlm.nih.gov/29808331/
  • 430. Janmejai K Srivastava,1,2,* Eswar Shankar,1,2 and Sanjay Gupta1,2,3, "Chamomile: A herbal medicine of the past with bright future", Journal List HHS Author Manuscripts PMC2995283. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995283/
  • 431. European Parliament News Headlines, "The impact of textile production and waste on the environment (infographic)", Society Updated: 26-04-2022 - 14:16 Created: 29-12-2020 - 08:00. https://www.europarl.europa.eu/news/en/headlines/society/20201208STO93327/the-impact-of-textile-production-and-waste-on-the-environment-infographic
  • 432. Cadles.org, "About the Candle Industry", FACTS & FIGURES. https://candles.org/facts-figures-2/
  • 433. Gaia Herbs, "Calm Kit", Home/Shop All/Stress Support/Calm Kit. https://www.gaiaherbs.com/products/calm-kit
  • 434. American Chemical Society, "Paleopharmaceuticals from Baltic amber might fight drug-resistant infections", ACS Discover Chemistry News Releases 2021 Paleopharmaceuticals from Baltic amber might fight drug-resistant infections. https://www.acs.org/pressroom/newsreleases/2021/april/paelopharmaceuticals-from-baltic-amber-might-fight-drug-resistant-infections.html
  • 435. Joseph Pizzorno, ND, "The Kidney Dysfunction Epidemic, Part 1: Causes", Journal List Integr Med (Encinitas) v.14(6); 2015 Dec PMC4718206. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718206/
  • 436. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), "Kidney Disease Statistics for the United States", Home Health Information Health Statistics Kidney Disease Statistics for the United States. https://www.niddk.nih.gov/health-information/health-statistics/kidney-disease
  • 437. Pulok K Mukherjee 1, Neelesh K Nema, Niladri Maity, Birendra K Sarkar, "Phytochemical and therapeutic potential of cucumber", Review Fitoterapia. 2013 Jan;84:227-36. doi: 10.1016/j.fitote.2012.10.003. Epub 2012 Oct 23.. https://pubmed.ncbi.nlm.nih.gov/23098877/
  • 1. Smith James, Belvin Jacob, "Somatic Symptoms with Psychogenic", Journal of Family Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138407
  • 438. L Ji 1, W Gao, J Wei, L Pu, J Yang, C Guo, "In Vivo Antioxidant Properties of Lotus Root and Cucumber: A Pilot Comparative Study in Aged Subjects", Randomized Controlled Trial J Nutr Health Aging. 2015 Aug;19(7):765-70. doi: 10.1007/s12603-015-0524-x.. https://pubmed.ncbi.nlm.nih.gov/26193861/
  • 439. Uzozie Chikere Ofoego1* Elizabeth Obioma Nweke2 Ogbonna Mishael Nzube1 1. Department of Anatomy, Faculty of Basic Medical Sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria 2. Department of Anatomy, Faculty of Basic Medical Sciences, Chukwuemeka Odumegwu Ojukwu University, Anambra State, Nigeria, "Ameliorative Effect of Ethanolic Extract of Cucumis Sativus (Cucumber) Pulp on Alloxan Induced Kidney Toxicity in Male Adult Wistar Rats", Journal of Natural Sciences Research www.iiste.org ISSN 2224-3186 (Paper) ISSN 2225-0921 (Online) DOI: 10.7176/JNSR Vol.9, No.4, 2019. https://core.ac.uk/download/pdf/234658074.pdf
  • 440. Gadah Albasher 1, Rafa Almeer 1, Saud Alarifi 1, Saad Alkhtani 1, Manal Farhood 1, Fatimah O Al-Otibi 2, Noorah Alkubaisi 2, Humaira Rizwana 2, "Nephroprotective Role of Beta vulgaris L. Root Extract against Chlorpyrifos-Induced Renal Injury in Rats", Evid Based Complement Alternat Med. 2019 Nov 22;2019:3595761. doi: 10.1155/2019/3595761. eCollection 2019.. https://pubmed.ncbi.nlm.nih.gov/31885644/
  • 441. Tarfa Albrahim 1, "Silver nanoparticles-induced nephrotoxicity in rats: the protective role of red beetroot (Beta vulgaris) juice", Environ Sci Pollut Res Int. 2020 Nov;27(31):38871-38880. doi: 10.1007/s11356-020-09671-7. Epub 2020 Jul 7.. https://pubmed.ncbi.nlm.nih.gov/32638302/
  • 442. Lavanya Cherukuri 1, Divya Birudaraju 1, April Kinninger 1, Bhanu T Chaganti 1, Chandana Shekar 1, Sajad Hamal 1, Kashif Shaikh 1, Ferdinand Flores 1, Sion K Roy 1, William Sotka 1, Shawn J Green 1, Matthew J Budoff 2, "Effect of a plant-based bioequivalent inorganic nitrate (NO3-) complex with vitamins, antioxidants and phytophenol rich food extracts in hypertensive individuals - A randomized, double-blind, placebo-controlled study", Randomized Controlled Trial Clin Nutr ESPEN. 2020 Dec;40:327-335. doi: 10.1016/j.clnesp.2020.08.007. Epub 2020 Sep 7.. https://pubmed.ncbi.nlm.nih.gov/33183558/
  • 443. Zahra Bahadoran 1, Parvin Mirmiran 2, Ali Kabir 3, Fereidoun Azizi 4, Asghar Ghasemi 5, "The Nitrate-Independent Blood Pressure-Lowering Effect of Beetroot Juice: A Systematic Review and Meta-Analysis", Review Adv Nutr. 2017 Nov 15;8(6):830-838. doi: 10.3945/an.117.016717. Print 2017 Nov.. https://pubmed.ncbi.nlm.nih.gov/29141968/
  • 444. Shaomin Zhao 1, Haiyan Liu 2, Liwei Gu 1, "American cranberries and health benefits - an evolving story of 25 years", Review J Sci Food Agric. 2020 Nov;100(14):5111-5116. doi: 10.1002/jsfa.8882. Epub 2018 Feb 20.. https://pubmed.ncbi.nlm.nih.gov/29315597/
  • 445. Lynda Frassetto 1, Ingrid Kohlstadt, "Treatment and prevention of kidney stones: an update", Review Am Fam Physician. 2011 Dec 1;84(11):1234-42.. https://pubmed.ncbi.nlm.nih.gov/22150656/
  • 446. Ioanna Vasileiou 1, Athanasios Katsargyris, Stamatios Theocharis, Constantinos Giaginis, "Current clinical status on the preventive effects of cranberry consumption against urinary tract infections", Review Nutr Res. 2013 Aug;33(8):595-607. doi: 10.1016/j.nutres.2013.05.018. Epub 2013 Jul 1.. https://pubmed.ncbi.nlm.nih.gov/23890348/
  • 447. Seyed Fazel Nabavi, Antoni Sureda, Maria Daglia, Morteza Izadi, Seyed Mohammad Nabavi 1, "Cranberry for Urinary Tract Infection: From Bench to Bedside", Review Curr Top Med Chem. 2017;17(3):331-339. doi: 10.2174/1568026616666160829161031.. https://pubmed.ncbi.nlm.nih.gov/27572082/
  • 448. Franck Bruyère 1 2, Abdel Rahmène Azzouzi 3, Jean-Philippe Lavigne 4 5, Stéphane Droupy 6, Patrick Coloby 7, Xavier Game 8, Gilles Karsenty 9, Bertrand Issartel 10, Alain Ruffion 11 12, Vincent Misrai 13, Albert Sotto 4 14, Francois-André Allaert 15 16, "A Multicenter, Randomized, Placebo-Controlled Study Evaluating the Efficacy of a Combination of Propolis and Cranberry (Vaccinium macrocarpon) (DUAB®) in Preventing Low Urinary Tract Infection Recurrence in Women Complaining of Recurrent Cystitis", Randomized Controlled Trial Urol Int. 2019;103(1):41-48. doi: 10.1159/000496695. Epub 2019 May 22.. https://pubmed.ncbi.nlm.nih.gov/31117097/
  • 449. Stacy L Haber 1, Kimberly A B Cauthon, Erin C Raney, "Cranberry and warfarin interaction: a case report and review of the literature", Review Consult Pharm. 2012 Jan;27(1):58-65. doi: 10.4140/TCP.n.2012.58.. https://pubmed.ncbi.nlm.nih.gov/22231999/
  • 450. Ajaz Ahmada, Pooja Kumarib, Masood Ahmadc, "Apigenin attenuates edifenphos-induced toxicity by modulating ROS-mediated oxidative stress, mitochondrial dysfunction and caspase signal pathway in rat liver and kidney", Pesticide Biochemistry and Physiology Volume 159, September 2019, Pages 163-172. https://www.sciencedirect.com/science/article/abs/pii/S0048357519302147
  • 451. Afifah Afifah, Fajar Wahyu Pribadi, Aulia Salsabiela, Dimo Hari Anggara, Zahra Muthmainnah Komara, Robby Al Fauzy, "The protective effect of celery ethanol extract on oxidative stress in chronic kidney disease rat model", Home Archives Vol. 41 No. 2 (2022) Original Articles. https://univmed.org/ejurnal/index.php/medicina/article/view/1265
  • 452. Maryam Hassanpour Moghadam, Mohsen Imenshahidi, and Seyed Ahmad Mohajeri, "Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration", Journal List J Med Food PMC3684138. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684138/
  • 453. Abdelkhalek Oussama 1, Mohamed Touhami, Mohamed Mbarki, "In vitro and in vivo study of effect of lemon juice on urinary lithogenesis", Arch Esp Urol. 2005 Dec;58(10):1087-92. doi: 10.4321/s0004-06142005001000019.. https://pubmed.ncbi.nlm.nih.gov/16482864/
  • 454. Kristina L Penniston 1, Thomas H Steele, Stephen Y Nakada, "Lemonade therapy increases urinary citrate and urine volumes in patients with recurrent calcium oxalate stone formation", Comparative Study Urology. 2007 Nov;70(5):856-60. doi: 10.1016/j.urology.2007.06.1115. Epub 2007 Oct 24.. https://pubmed.ncbi.nlm.nih.gov/17919696/
  • 455. Piero Ruggenenti 1 2, Maria Rosa Caruso 1, Monica Cortinovis 2, Annalisa Perna 2, Tobia Peracchi 2, Giovanni Antonio Giuliano 2, Stefano Rota 1, Paolo Brambilla 3, Giuliana Invernici 4, Davide Villa 2, Olimpia Diadei 2, Matias Trillini 2, Grazia Natali 1, Giuseppe Remuzzi 2, "Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial", EClinicalMedicine. 2021 Dec 14;43:101227. doi: 10.1016/j.eclinm.2021.101227. eCollection 2022 Jan.. https://pubmed.ncbi.nlm.nih.gov/34977512/
  • 456. American Thyroid Association (ATA), "Prevalence and Impact of Thyroid Disease", General Information/Press Room. https://www.thyroid.org/media-main/press-room/
  • 457. Cleveland Clinic medical professional, "Thyroid Disease", Home / Health Library / Disease & Conditions. https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease
  • 458. Cleveland Clinic medical professional, "Subclinical Hypothyroidism", Home / Health Library / Disease & Conditions. https://my.clevelandclinic.org/health/diseases/23544-subclinical-hypothyroidism
  • 459. American Thyroid Association (ATA), "Thyroid Function Tests", Home » Thyroid Function Tests. https://www.thyroid.org/thyroid-function-tests/
  • 460. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK),, "Thyroid Tests", Home / Health Information / Diagnostic Tests / Thyroid Tests. https://www.niddk.nih.gov/health-information/diagnostic-tests/thyroid
  • 461. Ashok Kumar Sharma 1, Indraneel Basu 1, Siddarth Singh 1, "Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial", Randomized Controlled Trial J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22.. https://pubmed.ncbi.nlm.nih.gov/28829155/
  • 462. Adrian L. Lopresti, PhD,a,b,∗ Stephen J. Smith, MA,a,b Hakeemudin Malvi, MBBS, MD,c and Rahul Kodgule, MBBSd, "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract", Journal List Medicine (Baltimore) v.98(37); 2019 Sep PMC6750292. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/#R20
  • 463. Shahad Imad, "Comparative Study between a Combination of Plants Extracts and Drugs on Thyroid Hormones and Lipid Profile in Experimental Animals", ResearchGate Home Shahad Imad. https://www.researchgate.net/profile/Shahad-Imad-2
  • 464. K Vondra 1, L Stárka, R Hampl, "Vitamin D and thyroid diseases", Review Physiol Res. 2015;64(Suppl 2):S95-S100. doi: 10.33549/physiolres.933083.. https://pubmed.ncbi.nlm.nih.gov/26680495/
  • 465. Dohee Kim 1 2, "The Role of Vitamin D in Thyroid Diseases", Review Int J Mol Sci. 2017 Sep 12;18(9):1949. doi: 10.3390/ijms18091949.. https://pubmed.ncbi.nlm.nih.gov/28895880/
  • 466. G Muscogiuri 1, G Tirabassi 2, G Bizzaro 3, F Orio 4, S A Paschou 5, A Vryonidou 5, G Balercia 2, Y Shoenfeld 6, A Colao 1, "Vitamin D and thyroid disease: to D or not to D?", Review Eur J Clin Nutr. 2015 Mar;69(3):291-6. doi: 10.1038/ejcn.2014.265. Epub 2014 Dec 17.. https://pubmed.ncbi.nlm.nih.gov/25514898/
  • 467. Juliana Soares Severo 1, Jennifer Beatriz Silva Morais 1, Taynáh Emannuelle Coelho de Freitas 1, Ana Letícia Pereira Andrade 1, Mayara Monte Feitosa 1, Larissa Cristina Fontenelle 1, Ana Raquel Soares de Oliveira 1, Kyria Jayanne Clímaco Cruz 1, Dilina do Nascimento Marreiro 1, "The Role of Zinc in Thyroid Hormones Metabolism", Int J Vitam Nutr Res. 2019 Jul;89(1-2):80-88. doi: 10.1024/0300-9831/a000262. Epub 2019 Apr 15.. https://pubmed.ncbi.nlm.nih.gov/30982439/
  • 468. Liliana R. Santos 1,2,3,Celestino Neves 4,5,Miguel Melo 1,5,6,7 andPaula Soares 1,3,5,, "Selenium and Seleno proteins in Immune Mediated Thyroid Disorders", Journals Diagnostics Volume 8 Issue 4 10.3390/diagnostics8040070. https://www.mdpi.com/2075-4418/8/4/70
  • 469. Johanna Wichman, Kristian Hillert Winther, Steen Joop Bonnema, and Laszlo Hegedüs, "Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis", Thyroid Vol. 26, No. 12Original Studies Thyroid Dysfunction: Hypothyroidism, Thyrotoxicosis, and Thyroid Function Tests. https://www.liebertpub.com/doi/10.1089/thy.2016.0256
  • 470. Michael I Liontiris 1, Elias E Mazokopakis, "A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients.Points that need more investigation", Review Hell J Nucl Med. 2017 Jan-Apr;20(1):51-56. doi: 10.1967/s002449910507. Epub 2017 Mar 20.. https://pubmed.ncbi.nlm.nih.gov/28315909/
  • 471. Javid Ghazizadeh 1 2 3, Saeed Sadigh-Eteghad 1, Wolfgang Marx 4, Ali Fakhari 5, Sanaz Hamedeyazdan 6, Mohammadali Torbati 7, Somaiyeh Taheri-Tarighi 1, Mostafa Araj-Khodaei 2 8, Mojgan Mirghafourvand 9, "The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis", Review Phytother Res. 2021 Dec;35(12):6690-6705. doi: 10.1002/ptr.7252. Epub 2021 Aug 27.. https://pubmed.ncbi.nlm.nih.gov/34449930/
  • 472. Andrew Scholey 1, Amy Gibbs 2, Chris Neale 3, Naomi Perry 4, Anastasia Ossoukhova 5, Vanessa Bilog 6, Marni Kras 7, Claudia Scholz 8, Mathias Sass 9, Sybille Buchwald-Werner 10, "Anti-stress effects of lemon balm-containing foods", Randomized Controlled Trial Nutrients. 2014 Oct 30;6(11):4805-21. doi: 10.3390/nu6114805.. https://pubmed.ncbi.nlm.nih.gov/25360512/
  • 473. David O Kennedy 1, Wendy Little, Andrew B Scholey, "Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)", Clinical Trial Psychosom Med. 2004 Jul-Aug;66(4):607-13. doi: 10.1097/01.psy.0000132877.72833.71.. https://pubmed.ncbi.nlm.nih.gov/15272110/
  • 474. Ali Zarei, Changizi-Ashtiyani, Soheila Taheri, Nasser Hosseini, "A Brief Overview of the Effects of Melissa officinalis L. Extract on the Function of Various Body Organs", Home / Journals / Zahedan Journal Of Research In Medical / Sciences / Articles. https://brieflands.com/articles/zjrms-1007.html#A1007REF26
  • 475. Ali Zarei, Saeed Changizi-Ashtiyani, R.A. Sokhandani, "The comparison of the alcholic extract effects of Mellissia officinalis and Atorvastatin on the serum levels of thyroid hormones in hypercholesterolemic male Rats", Home / Internal Medicine / Endocrinology / Medicine / Hormones / Thyroid Hormones. https://www.researchgate.net/publication/289541515_The_comparison_of_the_alcholic_extract_effects_of_Mellissia_officinalis_and_Atorvastatin_on_the_serum_levels_of_thyroid_hormones_in_hypercholesterolemic_male_Rats
  • 476. National Institute of Mental Health, "Anxiety Disorders", Home > Mental Health Information > Health Topics. https://www.nimh.nih.gov/health/topics/anxiety-disorders
  • 477. Maheep Bhatnagar 1, Durgesh Sharma, Mahendra Salvi, "Neuroprotective effects of Withania somnifera dunal.: A possible mechanism", Neurochem Res. 2009 Nov;34(11):1975-83. doi: 10.1007/s11064-009-9987-7. Epub 2009 May 15.. https://pubmed.ncbi.nlm.nih.gov/19444606/
  • 478. Jaysing Salve,1 Sucheta Pate,2 Khokan Debnath,3 and Deepak Lang, "Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study", Journal List Cureus v.11(12); 2019 Dec PMC6979308. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/
  • 479. Till Ittermann 1, Henry Völzke 2, Sebastian E Baumeister 2, Katja Appel 3, Hans J Grabe 3, "Diagnosed thyroid disorders are associated with depression and anxiety", Soc Psychiatry Psychiatr Epidemiol. 2015 Sep;50(9):1417-25. doi: 10.1007/s00127-015-1043-0. Epub 2015 Mar 17.. https://pubmed.ncbi.nlm.nih.gov/25777685/
  • 480. Mustafa Sait Gönen 1, Gurcan Kisakol, Ali Savas Cilli, Oguz Dikbas, Kagan Gungor, Ali Inal, Ahmet Kaya, "Assessment of anxiety in subclinical thyroid disorders", Endocr J. 2004 Jun;51(3):311-5. doi: 10.1507/endocrj.51.311.. https://pubmed.ncbi.nlm.nih.gov/15256776/
  • 481. Nearmeen M. Rashad MD & Ghada M. Samir, "Prevalence, risks, and comorbidity of thyroid dysfunction: a cross-sectional epidemiological study", Original article- Open Access- Published: 18 August 2020. https://ejim.springeropen.com/articles/10.4103/ejim.ejim_22_19
  • 482. K Chandrasekhar 1, Jyoti Kapoor, Sridhar Anishetty, "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults", Indian J Psychol Med. 2012 Jul;34(3):255-62. doi: 10.4103/0253-7176.106022.. https://pubmed.ncbi.nlm.nih.gov/23439798/
  • 483. Deepak Langade 1, Vaishali Thakare 2, Subodh Kanchi 3, Sunil Kelg, "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", Randomized Controlled Trial J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 484. Abhijit Deshpandea, Nushafreen Irania, Ratna BalkrishnanaIrin, Rosanna Bennyb, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Medicine Volume 72, August 2020, Pages 28-36. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 485. Joseph A. Hanson; Martin R. Huecker., "Sleep Deprivation", National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK547676/
  • 486. S K Bhattacharya 1, A Bhattacharya, K Sairam, S Ghosal, "Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study", Phytomedicine. 2000 Dec;7(6):463-9. doi: 10.1016/S0944-7113(00)80030-6.. https://pubmed.ncbi.nlm.nih.gov/11194174/
  • 487. James L Oschman 1, "Can electrons act as antioxidants? A review and commentary", Review J Altern Complement Med. 2007 Nov;13(9):955-67. doi: 10.1089/acm.2007.7048.. https://pubmed.ncbi.nlm.nih.gov/18047442/
  • 488. M Odell 1, "The human body as an electric circuit", J Clin Forensic Med. 1997 Mar;4(1):1-6. doi: 10.1016/s1353-1131(97)90001-8.. https://pubmed.ncbi.nlm.nih.gov/15335590/
  • 489. Gaétan Chevalier, 1, 2 , * Stephen T. Sinatra, 3 James L. Oschman, 4 Karol Sokal, 5 and Pawel Sokal 6, "Earthing: Health Implications of Reconnecting the Human Body to the Earth's Surface Electrons", Journal List J Environ Public Health v.2012; 2012 PMC3265077. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265077/
  • 490. Maurice Ghaly, Dale Teplitz, "The biologic effects of grounding the human body during sleep as measured by cortisol levels and subjective reporting of sleep, pain, and stress", J Altern Complement Med. 2004 Oct;10(5):767-76. doi: 10.1089/acm.2004.10.767.. https://pubmed.ncbi.nlm.nih.gov/15650465/
  • 491. Gaétan Chevalier, PhD,1 Stephen T. Sinatra, MD, FACC, FACN,2 James L. Oschman, PhD,corresponding author3 and Richard M. Delany, MD, FACC4, "Earthing (Grounding) the Human Body Reduces Blood Viscosity—a Major Factor in Cardiovascular Disease", Journal List J Altern Complement Med PMC3576907. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576907/
  • 492. Smith James, Belvin Jacob, "Earthing: Health Implications of Reconnecting the Human Body to the Earth's Surface Electrons", Journal of Family Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138407
  • 492. Gaétan Chevalier, PhD; Stephen T. Sinatra, MD, FACC, FACN, CNS, "Emotional Stress, Heart Rate Variability, Grounding, and Improved Autonomic Tone: Clinical Applications", Integrative Medicine • Vol. 10, No. 3 • Jun/Jul 2011. http://imjournal.com/pdfarticles/IMCJ10_3_p16_24chevalier.pdf
  • 493. Javid Ghazizadeh 1 2 3, Saeed Sadigh-Eteghad 1, Wolfgang Marx 4, Ali Fakhari 5, Sanaz Hamedeyazdan 6, Mohammadali Torbati 7, Somaiyeh Taheri-Tarighi 1, Mostafa Araj-Khodaei 2 8, Mojgan Mirghafourvand 9, "The effects of lemon balm (Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta-analysis", Review Phytother Res. 2021 Dec;35(12):6690-6705. doi: 10.1002/ptr.7252. Epub 2021 Aug 27.. https://pubmed.ncbi.nlm.nih.gov/34449930/
  • 494. Andrew Scholey 1, Amy Gibbs 2, Chris Neale 3, Naomi Perry 4, Anastasia Ossoukhova 5, Vanessa Bilog 6, Marni Kras 7, Claudia Scholz 8, Mathias Sass 9, Sybille Buchwald-Werner 10, "Anti-stress effects of lemon balm-containing foods", Randomized Controlled Trial Nutrients. 2014 Oct 30;6(11):4805-21. doi: 10.3390/nu6114805.. https://pubmed.ncbi.nlm.nih.gov/25360512/
  • 495. David O Kennedy 1, Wendy Little, Andrew B Scholey, "Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm)", Clinical Trial Psychosom Med . 2004 Jul-Aug;66(4):607-13. doi: 10.1097/01.psy.0000132877.72833.71.. https://pubmed.ncbi.nlm.nih.gov/15272110/
  • 496. Amy L Roe 1, Arvind Venkataraman 1, "The Safety and Efficacy of Botanicals with Nootropic Effects", Review Curr Neuropharmacol . 2021;19(9):1442-1467. doi: 10.2174/1570159X19666210726150432.. https://pubmed.ncbi.nlm.nih.gov/34315377/
  • 497. Philippe Aubert,1 Isabelle Guinobert,2,,3 Claude Blondeau,2,,3 Valérie Bardot,2,,3 Isabelle Ripoche,4 Pierre Chalard,4 and Michel Neunlist1, "Basal and Spasmolytic Effects of a Hydroethanolic Leaf Extract of Melissa officinalis L. on Intestinal Motility: An Ex Vivo Study", Journal List J Med Food PMC6653806. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653806/
  • 498. Smith James, Belvin Jacob, "Somatic Symptoms with Psychogenic", Journal of Family Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138407
  • 499. Suhrid Banskota 1, Jean-Eric Ghia 2, Waliul I Khan 3, "Serotonin in the gut: Blessing or a curse", Review Biochimie . 2019 Jun;161:56-64. doi: 10.1016/j.biochi.2018.06.008. Epub 2018 Jun 14.. https://pubmed.ncbi.nlm.nih.gov/29909048/
  • 500. Michelangelo Auteri 1, Maria Grazia Zizzo 1, Rosa Serio 2, "GABA and GABA receptors in the gastrointestinal tract: from motility to inflammation", Review Pharmacol Res. 2015 Mar;93:11-21. doi: 10.1016/j.phrs.2014.12.001. Epub 2014 Dec 17.. https://pubmed.ncbi.nlm.nih.gov/25526825/
  • 501. Carra A Simpson 1, Carmela Diaz-Arteche 2, Djamila Eliby 3, Orli S Schwartz 4, Julian G Simmons 3, Caitlin S M Cowan 5, "The gut microbiota in anxiety and depression - A systematic review", Review Clin Psychol Rev. 2021 Feb;83:101943. doi: 10.1016/j.cpr.2020.101943. Epub 2020 Oct 29.. https://pubmed.ncbi.nlm.nih.gov/33271426/
  • 502. Stefanie Malan-Muller 1, Mireia Valles-Colomer 2 3, Jeroen Raes 2 3, Christopher A Lowry 4 5 6 7 8, Soraya Seedat 1, Sian M J Hemmings 1, "The Gut Microbiome and Mental Health: Implications for Anxiety- and Trauma-Related Disorders", Review OMICS . 2018 Feb;22(2):90-107. doi: 10.1089/omi.2017.0077. Epub 2017 Aug 2.. https://pubmed.ncbi.nlm.nih.gov/28767318/
  • 503. Cleveland Clinic, "How Your Gut Microbiome Impacts Your Health", Health Essentials Newsletter June 9, 2022 / Digestive. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138407
  • 504. Elizabeth Thursby; Nathalie Juge, "Introduction to the human gut microbiota", Biochem J (2017) 474 (11): 1823–1836. https://doi.org/10.1042/BCJ20160510. https://portlandpress.com/biochemj/article/474/11/1823/49429/Introduction-to-the-human-gut-microbiota
  • 505. Tanja Sobko 1, Suisha Liang 2, Will H G Cheng 1, Hein M Tun 3 4, "Impact of outdoor nature-related activities on gut microbiota, fecal serotonin, and perceived stress in preschool children: the Play&Grow randomized controlled trial", Randomized Controlled Trial Sci Rep . 2020 Dec 15;10(1):21993. doi: 10.1038/s41598-020-78642-2.. https://pubmed.ncbi.nlm.nih.gov/33319792/
  • 506. Winfried E H Blum 1, Sophie Zechmeister-Boltenstern 1, Katharina M Keiblinger 2, "Does Soil Contribute to the Human Gut Microbiome?", Review Microorganisms. 2019 Aug 23;7(9):287. doi: 10.3390/microorganisms7090287.. https://pubmed.ncbi.nlm.nih.gov/31450753/
  • 507. Peter C Konturek 1, T Brzozowski, S J Konturek, "Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options", Review J Physiol Pharmacol. 2011 Dec;62(6):591-9.. https://pubmed.ncbi.nlm.nih.gov/22314561/
  • 508. Hang-Yu Li 1, Dan-Dan Zhou 1, Ren-You Gan 2 3, Si-Yu Huang 1, Cai-Ning Zhao 4, Ao Shang 1 5, Xiao-Yu Xu 1 5, Hua-Bin Li 1, "Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics on Metabolic Diseases Targeting Gut Microbiota: A Narrative Review", Review Nutrients. 2021 Sep 15;13(9):3211. doi: 10.3390/nu13093211.. https://pubmed.ncbi.nlm.nih.gov/34579087/
  • 509. Kathleen Lange 1, Martin Buerger, Andreas Stallmach, Tony Bruns, "Effects of Antibiotics on Gut Microbiota", Review Dig Dis. 2016;34(3):260-8. doi: 10.1159/000443360. Epub 2016 Mar 30.. https://pubmed.ncbi.nlm.nih.gov/27028893/
  • 510. Aadra P Bhatt 1, Dulan B Gunasekara 1, Jennifer Speer 1, Mark I Reed 1, Alexis N Peña 1, Bentley R Midkiff 2, Scott T Magness 3 4, Scott J Bultman 5 6, Nancy L Allbritton 1 3 6, Matthew R Redinbo 1 6 7, "Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells", ACS Infect Dis. 2018 Jan 12;4(1):46-52. doi: 10.1021/acsinfecdis.7b00139. Epub 2017 Nov 10.. https://pubmed.ncbi.nlm.nih.gov/29094594/
  • 511. Priyabrata Pattanayak 1, Pritishova Behera, Debajyoti Das, Sangram K Panda, "Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview", Pharmacogn Rev. 2010 Jan;4(7):95-105. doi: 10.4103/0973-7847.65323.. https://pubmed.ncbi.nlm.nih.gov/22228948/
  • 512. D Bhattacharyya 1, T K Sur, U Jana, P K Debnath, "Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorders", Controlled Clinical Trial Nepal Med Coll J. 2008 Sep;10(3):176-9.. https://pubmed.ncbi.nlm.nih.gov/19253862/
  • 513. Marc Maurice Cohen 1, "Tulsi - Ocimum sanctum: A herb for all reasons", Review J Ayurveda Integr Med. 2014 Oct-Dec;5(4):251-9. doi: 10.4103/0975-9476.146554.. https://pubmed.ncbi.nlm.nih.gov/25624701/
  • 514. Jack Feuer, "The Clutter Culture", UCLA Newsroom RSS. https://newsroom.ucla.edu/magazine/center-everyday-lives-families-suburban-america
  • 515. "Facts About Hypertension", Centers for Disease Control and Prevention. https://www.cdc.gov/bloodpressure/facts.htm
  • 516. Kulkarni S, O'Farrell I, Erasi M, Kochar MS, "Stress and hypertension", WMJ. 1998 Dec;97(11):34-8. PMID: 9894438.. https://pubmed.ncbi.nlm.nih.gov/9894438/
  • 517. Panossian A, Wikman G, "Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity", Pharmaceuticals. 2010; 3(1):188-224. https://doi.org/10.3390/ph3010188. https://www.mdpi.com/1424-8247/3/1/188
  • 518. Deshpande, A., Irani, N.,Balkrishnan, R.,Benny, IR, "A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults", Sleep Medicine, VOL.72, 2020/08/01, 1389-9457. https://www.sciencedirect.com/science/article/abs/pii/S1389945720301246
  • 519. Kaushik MK, Kaul SC, Wadhwa R, Yanagisawa M, Urade Y (2017), "Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction", PLoS ONE 12(2): e0172508.. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172508
  • 520. Dongre S, Langade D, Bhattacharyya S., "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study", Biomed Res Int. 2015;2015:284154. doi: 10.1155/2015/284154. Epub 2015 Oct 4. PMID: 26504795; PMCID: PMC4609357.. https://pubmed.ncbi.nlm.nih.gov/26504795/
  • 521. Lopresti AL, Drummond PD, Smith SJ, "A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males", American Journal of Men’s Health. 2019;13(2).. https://journals.sagepub.com/doi/full/10.1177/1557988319835985
  • 522. Brooks NA, Wilcox G, Walker KZ, Ashton JF, Cox MB, Stojanovska L, "Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content", Menopause. 2008 Nov-Dec;15(6):1157-62. doi: 10.1097/gme.0b013e3181732953. PMID: 18784609.. https://pubmed.ncbi.nlm.nih.gov/18784609/
  • 523. Sharma AK, Basu I, Singh S, "Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial", J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. PMID: 28829155.. https://pubmed.ncbi.nlm.nih.gov/28829155/
  • 524. Barja G, "Free radicals and aging", Trends Neurosci. 2004 Oct;27(10):595-600. doi: 10.1016/j.tins.2004.07.005. PMID: 15374670. https://pubmed.ncbi.nlm.nih.gov/15374670/
  • 525. Qin S, Huang L, Gong J, Shen S, Huang J, Ren H, Hu H, "Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials", Nutr J. 2017 Oct 11;16(1):68. doi: 10.1186/s12937-017-0293-y. PMID: 29020971; PMCID: PMC5637251.. https://pubmed.ncbi.nlm.nih.gov/29020971/
  • 526. Hadi A, Pourmasoumi M, Ghaedi E, Sahebkar A, "The effect of Curcumin/Turmeric on blood pressure modulation: A systematic review and meta-analysis", Pharmacol Res. 2019 Dec;150:104505. doi: 10.1016/j.phrs.2019.104505. Epub 2019 Oct 21. PMID: 31647981.. https://pubmed.ncbi.nlm.nih.gov/31647981/
  • 527. Ann F. Walker, Georgios Marakis, Andrew P. Morris, Paul A. Robinson, "Promising hypotensive effect of hawthorn extract: A randomized double-blind pilot study of mild, essential hypertension", https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.947
  • 528. Al-Gareeb, Ali, "Effect of hawthorn extract on blood pressure and lipid profile in patients with stage I hypertension: A placebo-controlled, double-blind randomized trial", https://www.researchgate.net/publication/274075458_Effect_of_hawthorn_extract_on_blood_pressure_and_lipid_profile_in_patients_with_stage_I_hypertension_A_placebo-controlled_double-blind_randomized_trial
  • 529. Keenan JM, Pins JJ, Frazel C, Moran A, Turnquist L, "Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial", J Fam Pract. 2002 Apr;51(4):369. PMID: 11978262.. https://pubmed.ncbi.nlm.nih.gov/11978262/
  • 530. Rayman MP, "The importance of selenium to human health", Lancet. 2000 Jul 15;356(9225):233-41. doi: 10.1016/S0140-6736(00)02490-9. PMID: 10963212.. https://pubmed.ncbi.nlm.nih.gov/10963212/
  • 531. Ahmed M. El-Sharkawy, Opinder Sahota, Dileep N. Lobo, "Acute and chronic effects of hydration status on health", Nutrition Reviews, Volume 73, Issue suppl_2, 1 September 2015, Pages 97–109. https://academic.oup.com/nutritionreviews/article/73/suppl_2/97/1930742?login=false
  • 532. "Blood Components", Community Blood Center. https://www.givingblood.org/about-blood/blood-components.aspx
  • 533. Green PJ, Kirby R, Suls J, "The effects of caffeine on blood pressure and heart rate: A review", Ann Behav Med. 1996 Sep;18(3):201-16. doi: 10.1007/BF02883398. PMID: 24203773.. https://pubmed.ncbi.nlm.nih.gov/24203773/
  • 534. Stone M, Ibarra A, Roller M, Zangara A, Stevenson E, "A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen", J Ethnopharmacol. 2009 Dec 10;126(3):574-6. doi: 10.1016/j.jep.2009.09.012. Epub 2009 Sep 23. PMID: 19781622.. https://pubmed.ncbi.nlm.nih.gov/19781622/
  • 535. Rodríguez-Huamán Á, Casimiro-Gonzales S, Chávez-Pérez JA, Gonzales-Arimborgo C, Cisneros-Fernández R, Aguilar-Mendoza LÁ, Gonzales GF, "Antioxidant and neuroprotector effect of Lepidium meyenii (maca) methanol leaf extract against 6-hydroxy dopamine (6-OHDA)-induced toxicity in PC12 cells", Toxicol Mech Methods. 2017 May;27(4):279-285. doi: 10.1080/15376516.2016.1275908. Epub 2017 Jan 8. PMID: 28007001.. https://pubmed.ncbi.nlm.nih.gov/28007001/
  • 536. Bonilla DA, Moreno Y, Gho C, Petro JL, Odriozola-Martínez A, Kreider RB, "Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis", J Funct Morphol Kinesiol. 2021 Feb 11;6(1):20. doi: 10.3390/jfmk6010020. PMID: 33670194; PMCID: PMC8006238.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006238/
  • 537. Langade D, Thakare V, Kanchi S, Kelgane S, "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study", J Ethnopharmacol. 2021 Jan 10;264:113276. doi: 10.1016/j.jep.2020.113276. Epub 2020 Aug 17. PMID: 32818573.. https://pubmed.ncbi.nlm.nih.gov/32818573/
  • 538. Ishaque S, Shamseer L, Bukutu C, Vohra S, "Rhodiola rosea for physical and mental fatigue: a systematic review", BMC Complement Altern Med. 2012 May 29;12:70. doi: 10.1186/1472-6882-12-70. PMID: 22643043; PMCID: PMC3541197.. https://pubmed.ncbi.nlm.nih.gov/22643043/
  • 539. Elkin HK, Winter A, "Grounding Patients With Hypertension Improves Blood Pressure: A Case History Series Study", Altern Ther Health Med. 2018 Nov;24(6):46-50. PMID: 30982019.. https://pubmed.ncbi.nlm.nih.gov/30982019/
  • 540. Chevalier G, Patel S, Weiss L, Chopra D, Mills PJ, "The Effects of Grounding (Earthing) on Bodyworkers' Pain and Overall Quality of Life: A Randomized Controlled Trial", Explore (NY). 2019 May-Jun;15(3):181-190. doi: 10.1016/j.explore.2018.10.001. Epub 2018 Oct 11. PMID: 30448083.. https://pubmed.ncbi.nlm.nih.gov/30448083/
  • 541. Ghaly M, Teplitz D, "The biologic effects of grounding the human body during sleep as measured by cortisol levels and subjective reporting of sleep, pain, and stress", J Altern Complement Med. 2004 Oct;10(5):767-76. doi: 10.1089/acm.2004.10.767. PMID: 15650465. https://pubmed.ncbi.nlm.nih.gov/15650465/
  • 542. Oschman JL, "Can electrons act as antioxidants? A review and commentary", J Altern Complement Med. 2007 Nov;13(9):955-67. doi: 10.1089/acm.2007.7048. PMID: 18047442.. https://pubmed.ncbi.nlm.nih.gov/18047442/
  • 543. Ideno Y, Hayashi K, Abe Y, Ueda K, Iso H, Noda M, Lee JS, Suzuki S, "Blood pressure-lowering effect of Shinrin-yoku (Forest bathing): a systematic review and meta-analysis", BMC Complement Altern Med. 2017 Aug 16;17(1):409. doi: 10.1186/s12906-017-1912-z. PMID: 28814305; PMCID: PMC5559777.. https://pubmed.ncbi.nlm.nih.gov/28814305/
  • 544. Summers JK, Vivian DN, "Ecotherapy - A Forgotten Ecosystem Service: A Review", Front Psychol. 2018 Aug 3;9:1389. doi: 10.3389/fpsyg.2018.01389. PMID: 30123175; PMCID: PMC6085576. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085576/
  • 545. Steptoe A, Gibson EL, Vuononvirta R, Williams ED, Hamer M, Rycroft JA, Erusalimsky JD, Wardle J, "The effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trial", Psychopharmacology (Berl). 2007 Jan;190(1):81-9. doi: 10.1007/s00213-006-0573-2. Epub 2006 Sep 30. PMID: 17013636.. https://pubmed.ncbi.nlm.nih.gov/17013636/
  • 546. Allison L. Hopkins, Marnie G. Lamm, Janet L. Funk, Cheryl Ritenbaugh,, "Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: A comprehensive review of animal and human studies", Fitoterapia,Volume 85,2013,Pages 84-94,ISSN 0367-326X,. https://www.sciencedirect.com/science/article/abs/pii/S0367326X13000063
  • 547. Da-Costa-Rocha I, Bonnlaender B, Sievers H, Pischel I, Heinrich M, "Hibiscus sabdariffa L. - a phytochemical and pharmacological review", Food Chem. 2014 Dec 15;165:424-43. doi: 10.1016/j.foodchem.2014.05.002. Epub 2014 May 27. PMID: 25038696.. https://pubmed.ncbi.nlm.nih.gov/25038696/
  • 548. Lezutekong JN, Nikhanj A, Oudit GY, "Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in cardiovascular disease", Clin Sci (Lond). 2018 Apr 30;132(8):901-904. doi: 10.1042/CS20180172. PMID: 29712884.. https://pubmed.ncbi.nlm.nih.gov/29712884/
  • 549. Ito M, Kusuhara S, Yokoi W, Sato T, Ishiki H, Miida S, Matsui A, Nakamori K, Nonaka C, Miyazaki K, "Streptococcus thermophilus fermented milk reduces serum MDA-LDL and blood pressure in healthy and mildly hypercholesterolaemic adults", Benef Microbes. 2017 Apr 26;8(2):171-178. doi: 10.3920/BM2016.0102. Epub 2017 Mar 16. PMID: 28299944.. https://pubmed.ncbi.nlm.nih.gov/28299944/
  • 550. Zhao X, Zhong X, Liu X, Wang X, Gao X, "Therapeutic and Improving Function of Lactobacilli in the Prevention and Treatment of Cardiovascular-Related Diseases: A Novel Perspective From Gut Microbiota", Front Nutr. 2021 Jun 7;8:693412. doi: 10.3389/fnut.2021.693412. PMID: 34164427; PMCID: PMC8215129.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8215129/
  • 551. Tang WH, Kitai T, Hazen SL., "Gut Microbiota in Cardiovascular Health and Disease", Circ Res. 2017 Mar 31;120(7):1183-1196. doi: 10.1161/CIRCRESAHA.117.309715. PMID: 28360349; PMCID: PMC5390330.. https://pubmed.ncbi.nlm.nih.gov/28360349/
  • 552. Peng Y, Ao M, Dong B, Jiang Y, Yu L, Chen Z, Hu C, Xu R, "Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures", Drug Des Devel Ther. 2021 Nov 2;15:4503-4525. doi: 10.2147/DDDT.S327378. PMID: 34754179; PMCID: PMC8572027.. https://pubmed.ncbi.nlm.nih.gov/34754179/
  • 553. Yan He, et al, "Curcumin, inflammation, and chronic disease: how at they linked?", PUbMed, May 2015. https://pubmed.ncbi.nlm.nih.gov/26007179/
  • 554. Erich Muhr, et al, "Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis", The Journal of Rheumatology, May 2002,. https://www.researchgate.net/publication/11416945_Randomized_double_blind_trial_of_an_extract_from_the_pentacyclic_alkaloid-chemotype_of_Uncaria_tomentosa_for_the_treatment_of_rheumatoid_arthritis
  • 555. Emilie Logie and Wim Vanden Berghe, "Tackling Chronic Inflammation with Withanolide Phytochemicals—A Withaferin A Perspective", PubMed Central, November 2020. https://pubmed.ncbi.nlm.nih.gov/33182809/
  • 556. Abudubari Sikandan, et al, "Ashwagandha root extract exerts anti‑inflammatory effects in HaCaT cells by inhibiting the MAPK/NF‑κB pathways and by regulating cytokines", PubMed, April 2, 2018. https://pubmed.ncbi.nlm.nih.gov/29620265/
  • 557. Tomokazu Ohishi, "Anti-inflammatory Action of Green Tea", PubMed, 2016. https://pubmed.ncbi.nlm.nih.gov/27634207/
  • 558. Megan E Cavet, et al, "Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells", PubMed, February 2011. https://pubmed.ncbi.nlm.nih.gov/21364905/#affiliation-1
  • 559. Xuesheng Han, "Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano ( Origanum vulgare) essential oil in a human skin disease model", PubMed, June 2017. https://pubmed.ncbi.nlm.nih.gov/29450144/
  • 560. Vidhya Rathnavelu, et al,, "Potential role of bromelain in clinical and therapeutic applications", PubMed, July 18, 2016. https://pubmed.ncbi.nlm.nih.gov/27602208/
  • 561. Reinhard Grzanna et al, "Ginger--an herbal medicinal product with broad anti-inflammatory actions", PubMed, Summer 2005. https://www.https://pubmed.ncbi.nlm.nih.gov/16117603/.nlm.nih.gov/pmc/articles/PMC8138407
  • 562. Mariangela Rondanelli et al, "Clinical trials on pain lowering effect of ginger: A narrative review", PubMed, November 2020. https://pubmed.ncbi.nlm.nih.gov/32436242/